Odontogenic myxoma: an updated analysis of 1,692 cases reported in the literature

dc.creatorBruno Ramos Chrcanovic
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2025-01-28T13:14:20Z
dc.date.accessioned2025-09-09T00:52:34Z
dc.date.available2025-01-28T13:14:20Z
dc.date.issued2019-04
dc.identifier.doihttps://doi.org/10.1111/odi.12875
dc.identifier.issn1601-0825
dc.identifier.urihttps://hdl.handle.net/1843/79508
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral Diseases
dc.rightsAcesso Restrito
dc.subjectOdontogenic tumors
dc.subjectClinical study
dc.subjectRadiology
dc.subjectRoot resorption
dc.subjectRecurrence
dc.subject.otherClinical features
dc.subject.otherFibromyxoma
dc.subject.otherMyxofibroma
dc.subject.otherOdontogenic myxoma
dc.subject.otherOdontogenic tumors
dc.subject.otherRecurrence rate
dc.titleOdontogenic myxoma: an updated analysis of 1,692 cases reported in the literature
dc.typeArtigo de periódico
local.citation.epage683
local.citation.issue3
local.citation.spage676
local.citation.volume25
local.description.resumoThe aim of the present study was to integrate the available data published on odontogenic myxoma (OM) into a comprehensive analysis of its clinical/radiological features. Electronic search undertaken in January/2018, looking for publications reporting cases of OM. A total of 377 publications were included. We identified 1,692 lesions, and 695 were used for the analysis of recurrence. There is a predominance of OMs in females and in mandibles. OMs usually present with bone expansion, asymptomatic cortical perforation, and a multilocular appearance. Lesion location (maxilla/mandible), bone expansion, cortical bone perforation, locular radiological appearance, tooth resorption, odontogenic epithelial rests, or angular septa are not associated with recurrence. While curettage (31.3%) showed the highest recurrence rate, marginal resection (1.3%) and segmental resection (3.1%) showed the lowest values. Enucleation + peripheral osteotomy (6.7%) showed better results than enucleation (13.1%) or enucleation + curettage (12.7%). In comparison with unilocular lesions, multilocular ones were significantly more prevalent in mandibles, more often presented expansion and cortical bone perforation, had larger mean size, and were more often treated by segmental resection. Conservative surgical procedures are associated with higher probability of recurrence of OM. Taking into consideration the recurrence rate and morbidity associated with different surgical treatments, tumor enucleation followed by peripheral osteotomy should be considered as the first therapeutic choice.
local.identifier.orcidhttps://orcid.org/0000-0002-3460-3374
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/odi.12875

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