Resistência à insulina em Comunidades Rurais do Vale do Jequitinhonha - Minas Gerais

Abstract

The insulin resistance can be defined by a diminished response to the biological actions of the insulin. This abnormality occurs mainly due to an improper action of this hormone in peripheral tissues such as: fat, muscular and liver tissues. Some studies has shown that the fat tissue acts increasing the demand for insulin and at the same time creating a resistance to it, and this leads to glycemia increase, and consequently leads to hyperinsulinemia; this can progress to type 2 diabetes. The purpose of this study was to verify the association of anthropometric, biochemical, and hemodynamics indicators with the insulin resistance in adults in two rural communities of Vale do Jequitinhonha, Minas Gerais. The sample was composed by individuals with 18 years of age or older, from both sex and living at least two years at the community. Pregnant women and diabetic individuals were excluded. Data collection included demographic, lifestyle, hemodynamics, anthropometric, body composition and biochemical variables. Data was processed in Statistical Software for Professionals (STATA) 9.0. From the 567 individuals, 50.4% were men and 49.6% were women, the age varied between 18 and 94 years. The major part of the people consisted of individuals of black skin (75.7%), lived with their couple (69.3%), had a low educational level, they were not either smokers or had the habit of drink alcoholic drinks. In this search 24.2% of the studied population was resistant to insulin, 17.4% presented overweight, and 5.5% were obese. By the multivariate analysis we could see that for adults, non diabetic, with low socioeconomic and educational level, the factors associated to the insulin resistance were overweight and obesity, the waist to hip ratio increase, reactive protein C and the individuals skin color.