Salivary gland cancer in southern Brazil: a prognostic study of 107 cases

Página do item simplificado
dc.creatorVirgilio Gonzales Zanella
dc.creatorPablo Agustin Vargas
dc.creatorManoela Domingues Martins
dc.creatorVivian Petersen Wagner
dc.creatorTuany Rafaeli Schmidt
dc.creatorStefanie Thieme
dc.creatorCintia Correa
dc.creatorFelipe Paiva Fonseca
dc.creatorPettala Rigon
dc.creatorMarinez Bizarro Barra
dc.creatorRicardo Gallicchio Kroef
dc.date.accessioned2023-12-06T20:31:25Z
dc.date.accessioned2025-09-09T00:21:12Z
dc.date.available2023-12-06T20:31:25Z
dc.date.issued2020-11-28
dc.identifier.doihttps://doi.org/10.4317%2Fmedoral.24248
dc.identifier.issn16986946
dc.identifier.urihttps://hdl.handle.net/1843/61821
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMedicina Oral Patologia Oral y Cirugia Bucal
dc.rightsAcesso Aberto
dc.subjectHead and neck neoplasms
dc.subjectEpithelial cells
dc.subjectRare diseases
dc.subjectEpidemiology
dc.subjectPrognosis
dc.subjectRecurrence
dc.subjectCarcinoma
dc.subjectSurvival
dc.subject.othertítulo periódico Medicina oral patologia oral y cirugia bucal busca dia 24 do mes 11 ano 2023 fao clínica open acess assunto Head and Neck Neoplasms
dc.subject.otherSalivary gland cancer in southern brazil: a prognostic study of 107 cases título periódico Medicina oral patologia oral y cirugia bucal busca dia 24 do mes 11 ano 2023 fao clínica open acess assunto Head and Neck Neoplasms
dc.titleSalivary gland cancer in southern Brazil: a prognostic study of 107 cases
dc.typeArtigo de periódico
local.citation.epagee403
local.citation.issue3
local.citation.spagee393
local.citation.volume26
local.description.resumoBackground: Salivary gland cancers (SGC) represent an uncommon group of heterogeneous tumors. We performed a retrospective survey of SGC diagnosed in a reference center for treatment of malignant tumors from the south of Brazil aiming to determine the prognostic value of demographic, clinic and pathologic features. Material and methods: Cases diagnosed as SGC between 2006 and 2016 were retrospectively collected. Medical records were examined to extract demographic, clinic, pathologic and follow-up information. Results: One-hundred and seven cases of SGC were identified. The most common SGC were mucoepidermoid carcinoma (MEC) (n = 39) followed by adenoid cystic carcinoma (AdCC) (n = 29). Among AdCCs, 55.2% of cases were classified as cribriform, 27.6% as tubular and 17.2% as solid. The tubular subtype had the highest percentage of cases with perineural invasion (p=0.01). Among MEC, 61.5% of cases were classified as low grade, 15.4% as intermediate grade and 19.9% as high grade. Low grade MEC had the lowest percentage of cases with perineural invasion (p=0.04). The 5-year survival for loco-regional control, disease-free survival (DFS) and disease-specific survival were 75%, 70% and 84%, respectively. The following features were associated with poor DFS: advanced age (p=0.03), rural residency (p=0.01), being a smoker or former smoker (p=0.01), pain (p=0.03), nodal metastasis (p<0.001), need for chemotherapy (p=0.02), neck dissection (p=0.04), perineural invasion (p=0.01), and being diagnosed with AdCC compared to MEC (p=0.02). Conclusions: The clinco-demographic and pathologic features identified as prognostic factors reveal the profile of patients at increased risk of recurrence and who would benefit from closer follow-up.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141320/

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Salivary gland cancer in Southern Brazil a prognostic study of 107 cases.pdf
Tamanho:
2.27 MB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG