Association between the use of female hormones and the thrombin generation: cross-sectional analysis of the longitudinal study on adult health (ELSA-Brasil)
| dc.creator | Thaís Resendebatista | |
| dc.creator | Sandhi Maria Barreto | |
| dc.creator | Ana Paula Ferreira Silva | |
| dc.creator | Wander Valadares de Oliveira Junior | |
| dc.creator | Chams Bicalho Maluf | |
| dc.creator | Antonio Luiz Pinho Ribeiro | |
| dc.creator | Maria Das Graças Carvalho | |
| dc.creator | Roberta Carvalho de Figueiredo | |
| dc.creator | Danyelle Romana Alves Rios | |
| dc.date.accessioned | 2023-05-17T19:25:03Z | |
| dc.date.accessioned | 2025-09-09T00:55:13Z | |
| dc.date.available | 2023-05-17T19:25:03Z | |
| dc.date.issued | 2021-03-08 | |
| dc.description.abstract | Introdução: O teste de geração de trombina (TGT) avalia o risco de desenvolvimento de eventos trombóticos. O objetivo deste estudo foi investigar a associação entre o uso de contraceptivos orais (COs) e a terapia hormonal (TH)com a TGT e a resistência à proteína C ativada (PCa). Métodos: Estudo transversal com mulheres do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). A TGT foi realizada pelo método CAT. Resultados: Houve associação entre todos os parâmetros do TGT e o uso de COs e associação do tempo de latência e pico com o uso de TH. Conclusão: A TGT permite avaliar o estado de hipercoagulabilidade e pode ser útil no manejo de usuárias de hormônios femininos | |
| dc.format.mimetype | ||
| dc.identifier.doi | 10.33448/rsd-v10i9.17888 | |
| dc.identifier.issn | 25253409 | |
| dc.identifier.uri | https://hdl.handle.net/1843/53504 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.relation.ispartof | Research, Society and Development | |
| dc.rights | Acesso Aberto | |
| dc.subject | Anticoncepcionais Orais | |
| dc.subject | Terapia de Reposição Hormonal | |
| dc.subject | Testes de Coagulação Sanguínea | |
| dc.subject.other | Contraceptives, | |
| dc.subject.other | Oral | |
| dc.subject.other | Hormone replacement therapy | |
| dc.subject.other | Blood coagulation tests | |
| dc.title | Association between the use of female hormones and the thrombin generation: cross-sectional analysis of the longitudinal study on adult health (ELSA-Brasil) | |
| dc.title.alternative | Associação entre o uso de contraceptivos orais e terapia hormonal e a geração de trombina: Análise transversal do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 22 | |
| local.citation.issue | 9 | |
| local.citation.spage | 1 | |
| local.citation.volume | 10 | |
| local.description.resumo | Introduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CAT method. Results: There was an association between all parameters of the TGA and the use of OCs and an association of lag time and peak time with the use of HT. Conclusion: The TGA allows us to assess the hypercoagulability status and may be useful in the management of female hormones users. | |
| local.identifier.orcid | https://orcid.org/0000-0002-3690-2554 | |
| local.publisher.country | Brasil | |
| local.publisher.department | MED - DEPARTAMENTO DE CLÍNICA MÉDICA | |
| local.publisher.department | MED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR | |
| local.publisher.initials | UFMG | |
| local.url.externa | https://rsdjournal.org/index.php/rsd/article/view/17888 |