Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats

Página do item simplificado
dc.creatorMarina Carminatti
dc.creatorFrancine Benetti
dc.creatorRenato Luiz Siqueira
dc.creatorEdgar Dutra Zanotto
dc.creatorAndré Luiz Fraga Briso
dc.creatorAntônio Hernandes Chaves-Neto
dc.creatorLuciano Tavares Ângelo Cintra
dc.date.accessioned2022-11-29T21:34:22Z
dc.date.accessioned2025-09-09T00:32:45Z
dc.date.available2022-11-29T21:34:22Z
dc.date.issued2020-06-08
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1590/1678-7757-2019-0384
dc.identifier.issn16787765
dc.identifier.urihttps://hdl.handle.net/1843/47551
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Applied Oral Science
dc.rightsAcesso Aberto
dc.subjectDental pulp
dc.subjectHydrogen peroxide
dc.subjectTooth bleaching
dc.subjectTooth remineralization
dc.subject.otherBioactive glass
dc.subject.otherDental pulp
dc.subject.otherHydrogen peroxide
dc.subject.otherTooth bleaching.
dc.subject.otherTooth remineralization
dc.titleExperimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
dc.typeArtigo de periódico
local.citation.epage10
local.citation.spage01
local.citation.volume28
local.description.resumoObjectives This study evaluated if the use of a bioactive glass-ceramic-based gel, named Biosilicate (BS), before, after or mixed with bleaching gel, could influence the inflammation of the dental pulp tissue of rats’ molars undergoing dental bleaching with hydrogen peroxide (H2O2). Methodology The upper molars of Wistar rats (Rattus norvegicus, albinus) were divided into Ble: bleached (35% H2O2, 30-min); Ble-BS: bleached and followed by BS-based gel application (20 min); BS-Ble: BS-based gel application and then bleaching; BS/7d-Ble: BS-based gel applications for 7 days and then bleaching; Ble+BS: blend of H2O2 with BS-based gel (1:1, 30-min); and control: placebo gel. After 2 and 30 days (n=10), the rats were euthanized for histological evaluation. The Kruskal-Wallis and Dunn statistical tests were performed (P<0.05). Results At 2 days, the Ble and Ble-BS groups had significant alterations in the pulp tissue, with an area of necrosis. The groups with the application of BS-based gel before H2O2 had moderate inflammation and partial disorganization in the occlusal third of the coronary pulp and were significantly different from the Ble in the middle and cervical thirds (P<0.05). The most favorable results were observed in the Ble+BS, which was similar to the control in all thirds of the coronary pulp (P>0.05). At 30 days, the pulp tissue was organized and the bleached groups presented tertiary dentin deposition. The Ble group had the highest deposition of tertiary dentin, followed by the Ble-BS, and both were different from control (P<0.05). Conclusion A single BS-based gel application beforehand or BS-based gel blended with a bleaching gel minimize the pulp damage induced by dental bleaching.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/jaos/a/rWmYM9cjZDtHyVFpBKNKDyf/?lang=en

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats.pdf
Tamanho:
2.91 MB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG