Cost analysis of smear microscopy and the xpert assay for tuberculosis diagnosis: average turnaround time

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dc.creatorLida Jouca
dc.creatorCristiane Aparecida Menezes de Pádua
dc.creatorIsabela Neves de Almeida
dc.creatorSilvana Spindola de Miranda
dc.creatorLucas Benício Dos Santos
dc.creatorCaroline Gontijo
dc.creatorValéria Martins Soares
dc.creatorSuely Alves
dc.creatorMaria c. Vater
dc.creatorAfranio Kritski
dc.creatorWânia da Silva Carvalho
dc.date.accessioned2024-01-12T22:40:53Z
dc.date.accessioned2025-09-08T23:12:43Z
dc.date.available2024-01-12T22:40:53Z
dc.date.issued2020
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0314-2020
dc.identifier.issn16789849
dc.identifier.urihttps://hdl.handle.net/1843/62757
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical
dc.rightsAcesso Aberto
dc.subjectMycobacterium tuberculosis
dc.subjectMolecular Diagnostic Techniques
dc.subjectTuberculosis, Pulmonary
dc.subjectCosts and Cost Analysis
dc.subjectHealth Systems
dc.subject.otherMycobacterium tuberculosis
dc.subject.otherMolecular diagnostic
dc.subject.otherTuberculosis, Pulmonary
dc.subject.otherCost Analysis
dc.subject.otherHealth Systems
dc.titleCost analysis of smear microscopy and the xpert assay for tuberculosis diagnosis: average turnaround time
dc.typeArtigo de periódico
local.citation.epage6
local.citation.issuee20200314
local.citation.spage1
local.citation.volume53
local.description.resumoIntroduction: Rapid and accurate tuberculosis detection is critical for improving patient diagnosis and decreasing tuberculosis transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time and economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate the cost and average turnaround time of smear microscopy and Xpert assay at a university hospital. Methods: The turnaround time and cost of the laboratory diagnosis of tuberculosis were calculated based on the mean cost and activity based costing (ABC). Results: The average turnaround time for smear microscopy was 16.6 hours while that for Xpert was 24.1 hours. The Xpert had a mean cost of USD 17.37 with an ABC of USD 10.86, while smear microscopy had a mean cost of USD 13.31 with an ABC of USD 6.01. The sensitivity of smear microscopy was 42.9% and its specificity was 99.1%, while the Xpert assay had a sensitivity of 100% and a specificity of 96.7%. Conclusions: The Xpert assay has high accuracy; however, the turnaround time and cost of smear microscopy were lower than those of Xpert.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIAL
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0037-8682-0314-2020

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