Data on statistical experimental design to formulate amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid for the treatment of vulvovaginal candidiasis

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dc.creatorCarolina Mirtes Melo
dc.creatorJéssica Ferreira Cardoso
dc.creatorFernanda Barçante Perasoli
dc.creatorMaria Betânia de Freitas Marques
dc.creatorWagner da Nova Mussel
dc.creatorSandra Aparecida de Lima Moura
dc.creatorGisele Rodrigues da Silva
dc.date.accessioned2022-04-01T22:08:11Z
dc.date.accessioned2025-09-09T00:42:33Z
dc.date.available2022-04-01T22:08:11Z
dc.date.issued2020-04
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doi10.1016/j.dib.2020.105311
dc.identifier.issn2352-3409
dc.identifier.urihttps://hdl.handle.net/1843/40712
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofData in Brief
dc.rightsAcesso Aberto
dc.subjectCandidíase vulvovaginal
dc.subject.otherHyaluronic acid
dc.subject.otherAmphotericin B
dc.subject.otherAmphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid
dc.subject.otherEudragit RL100
dc.subject.otherVulvovaginal candidiasis
dc.titleData on statistical experimental design to formulate amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid for the treatment of vulvovaginal candidiasis
dc.typeArtigo de periódico
local.citation.epage22
local.citation.spage1
local.citation.volume29
local.description.resumoData described in this article are related to the research article entitled “Amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid (AMP EUD nanoparticles/HA) for the treatment of vulvovaginal candidiasis”. In this work, we report original data on the statistical experimental design to formulate uncoated AMP EUD nanoparticles, data on the validation of spectrophotometric method to quantify the AMP released from uncoated EUD nanoparticles and coated with HA to obtain the in vitro drug release profiles as well as the drug encapsulation efficiency. In addition, we describe original data on characterization, including diameter size, polydispersity index, zeta potential, FTIR, DSC/TG, and XRD; data on diameter of in vitro inhibition halos of Candida albicans; and on the vaginal burden of infected animals treated with uncoated AMP EUD nanoparticles and AMP EUD nanoparticles/HA. Finally, different histological sections of endocervix collected from treated and untreated animals were inserted into this manuscript.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2352340920302055?via%3Dihub

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