Meningoencefalomielite de origem desconhecida em um cão – revisão e relato de caso

Abstract

Meningoencephalomyelitis of unknown origin (MUO) are diseases well known in literature. They are defined as idiopathic inflammatory non infectious diseases of the canine central nervous system. MUO occurs predominantly in small dog breeds of dogs, approximately five years old, varying between breeds and according the specific disorder. They cause multifocal lesions with varied topography, although it is predictable for each kind of MUO. Clinical signs are related to the topography of the lesion and are varied, including depression of consciousness, circling, seizures, cervical spinal hyperesthesia, proprioceptive deficit, ataxia, etc. Diagnosis is based on history and anamnesis, exclusion of infectious diseases, neuroimaging findings and cerebrospinal fluid abnormalities. Definitive diagnosis is based on histopathology, frequently obtained only after animal death. Primary treatment of MUOs is immunosuppression and there are several protocols. This monograph has the objective of a small review about meningoencephalomyelitis and MUOs, as well as to describe a suspicious case report.