T-cell/histiocyte-rich large b-cell lymphoma: report of the first case in the mandible

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dc.creatorRicardo Natã Fonseca Silva
dc.creatorAline Carvalho Batista
dc.creatorRita de Cássia Gonçalves Alencar
dc.creatorRicardo Alves de Mesquita
dc.creatorNadia Lago Costa
dc.creatorElismauro Francisco Mendonça
dc.date.accessioned2024-10-21T22:11:37Z
dc.date.accessioned2025-09-09T00:14:22Z
dc.date.available2024-10-21T22:11:37Z
dc.date.issued2018-07-17
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1007/s12105-018-0948-9
dc.identifier.issn1936-0568
dc.identifier.urihttps://hdl.handle.net/1843/77556
dc.languagepor
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofHead and Neck Pathology
dc.rightsAcesso Restrito
dc.subjectJaw
dc.subjectLymphoma, non-hodgkin
dc.subjectLymphoma
dc.subjectLymphoma, large b-cell, diffuse
dc.subjectPeriapical diseases
dc.subjectEdema
dc.subjectTherapeutics
dc.subjectMandible
dc.subjectMaxilla
dc.subject.otherJaw
dc.subject.otherLymphoma
dc.subject.otherNon-hodking
dc.subject.otherLarge b cell
dc.subject.otherDiffuse
dc.subject.otherPeriapical diseases
dc.titleT-cell/histiocyte-rich large b-cell lymphoma: report of the first case in the mandible
dc.typeArtigo de periódico
local.citation.epage717
local.citation.spage711
local.citation.volume13
local.description.resumoT-cell/histiocyte-rich large B-cell lymphoma (THRBCL) is an uncommon subtype of non-Hodgkin’s lymphoma. It is a predominant nodal neoplasm; however, extranodal sites, such as the spleen, liver and bone marrow, can be involved at diagnosis. However, only one case of primary THRLBCL in the jaws have been reported. We herein describe a 29-year-old female patient who presented with a swelling of the right mandible that had grown rapidly over the previous 2 months. Periapical and panoramic radiographs showed a multilocular osteolytic lesion located in the mandibular periapical region of the canine and premolar teeth and molar region. Preoperative examination and incisional biopsy were performed. Immunohistochemistry was applied to confirm the diagnosis of THRBCL in the jaw. The treatment consisted of CHOP therapy and radiotherapy. After complete tumor remission following initial treatment, additional sites of the disease appeared in the lung, abdomen and long bones. The patient died within 2 months. THRLBCL is an uncommon and aggressive malignant neoplasm that can involve the jaws, mimicking a periapical disease.
local.identifier.orcidhttps://orcid.org/0000-0002-2117-5593
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.identifier.orcidhttps://orcid.org/0000-0003-0198-5828
local.identifier.orcidhttps://orcid.org/0000-0002-6751-3279
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s12105-018-0948-9

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