Cell phone use is associated with an inflammatory cytokine profile of parotid gland saliva

Página do item simplificado
dc.creatorElisa Carvalho de Siqueira
dc.creatorFabrício Tinôco Alvim de Souza
dc.creatorEfigênia Ferreira Ferreira
dc.creatorRenan Pedra Souza
dc.creatorEitan Friedman
dc.creatorMarcus Vinícius Gomez
dc.creatorCarolina Cavalieri Gomes
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2025-06-03T20:35:57Z
dc.date.accessioned2025-09-08T22:49:48Z
dc.date.available2025-06-03T20:35:57Z
dc.date.issued2016-10
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/jop.12434
dc.identifier.issn1600-0714
dc.identifier.urihttps://hdl.handle.net/1843/82759
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Oral Pathology & Medicine
dc.rightsAcesso Aberto
dc.subjectInflammation
dc.subjectSaliva
dc.subjectCytokines
dc.subjectInterleukin-6
dc.subjectTumor necrosis factor-alpha
dc.subjectInterferon-gamma
dc.subjectParotid gland
dc.subjectThermogenesis
dc.subjectInterleukin-10
dc.subjectInterleukin-1beta
dc.subject.otherInterleukin-1beta
dc.subject.otherInflammation
dc.subject.otherinterleukin 10
dc.subject.otherMolecular alteration
dc.subject.otherNon-ionizing radiation
dc.titleCell phone use is associated with an inflammatory cytokine profile of parotid gland saliva
dc.typeArtigo de periódico
local.citation.epage686
local.citation.issue9
local.citation.spage682
local.citation.volume45
local.description.resumoBackground: There is controversy on the effects of the non-ionizing radiation emitted by cell phones on cellular processes and the impact of such radiation exposure on health. The purpose of this study was to investigate whether cell phone use alters cytokine expression in the saliva produced by the parotid glands. Methods: Cytokine expression profile was determined by enzyme linked immuno sorbent assay (ELISA) in the saliva produced by the parotid glands in healthy volunteers, and correlated with self-reported cell phone use and laterality. Results: The following parameters were determined, in 83 Brazilian individuals in saliva produced by the parotid glands comparing the saliva from the gland exposed to cell phone radiation (ipsilateral) to that from the contralateral parotid: salivary flow, total protein concentration, interleukin 1 β (IL-1 β), interleukin 6 (IL-6), interleukin 10 (IL-10), interferon γ (IFN-γ), and tumor necrosis factor α (TNF-α) salivary levels by ELISA. After multiple testing correction, decreased IL-10 and increased IL-1β salivary levels in the ipsilateral side compared with the contralateral side (P < 0.05) were detected. Subjects who used cell phones for more than 10 years presented higher differences between IL-10 levels in ipsilateral versus contralateral parotids (P = 0.0012). No difference was observed in any of the tested parameters in correlation with cell phone monthly usage in minutes. Conclusion: The exposure of parotid glands to cell phones can alter salivary IL-10 and IL-1β levels, consistent with a pro-inflammatory microenvironment that may be related to heat production.
local.identifier.orcidhttps://orcid.org/0000-0002-3005-1736
local.identifier.orcidhttps://orcid.org/0000-0002-0732-7183
local.identifier.orcidhttps://orcid.org/0000-0002-0665-211X
local.identifier.orcidhttps://orcid.org/0000-0002-9479-4432
local.identifier.orcidhttps://orcid.org/0000-0002-6745-1733
local.identifier.orcidhttps://orcid.org/0000-0002-6082-930X
local.identifier.orcidhttps://orcid.org/0000-0003-1580-4995
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVA
local.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIA
local.publisher.departmentICB - DEPARTAMENTO DE PATOLOGIA
local.publisher.departmentFAO - FACULDADE DE ODONTOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12434

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG