Incidence and risk factors for hyperglycemia in pregnancy among nulliparous women: a brazilian multicenter cohort study

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dc.creatorBianca F.nicolosi
dc.creatorPhilip n. Baker
dc.creatorLouise c. Kenny
dc.creatorJose g. Cecatti
dc.creatorIracema m. Calderon
dc.creatorRenato t. Souza
dc.creatorJussara de Souza Mayrink Novais
dc.creatorFrancisco e. Feitosa
dc.creatorEdilberto a. Rocha Filho
dc.creatorDébora f. Leite
dc.creatorJanete Vettorazzi
dc.creatorMaria h. Sousa
dc.creatorMaria l. Costa
dc.date.accessioned2023-11-06T19:52:51Z
dc.date.accessioned2025-09-09T00:21:19Z
dc.date.available2023-11-06T19:52:51Z
dc.date.issued2020
dc.format.mimetypepdf
dc.identifier.doi10.1371/journal.pone.0232664
dc.identifier.issn19326203
dc.identifier.urihttps://hdl.handle.net/1843/60504
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofPLoS One
dc.rightsAcesso Aberto
dc.subjectHyperglycemia
dc.subjectPregnancy
dc.subjectDiabetes, Gestational
dc.subject.otherHyperglycemia
dc.subject.otherPregnancy
dc.subject.otherDiabetes, Gestational
dc.titleIncidence and risk factors for hyperglycemia in pregnancy among nulliparous women: a brazilian multicenter cohort study
dc.typeArtigo de periódico
local.citation.epage14
local.citation.spage1
local.citation.volume15
local.description.resumoObjective:To assess the incidence and risk factors for hyperglycemia in pregnancy in a cohort of Bra zilian nulliparous pregnant women.Materials and methods:This is a secondary analysis of a multicenter cohort study that enrolled 1,008 nulliparous pregnant women at 19–21 weeks. Exclusion criteria included chronic exposure to corticosteroids and previous diabetes. Bivariate and multivariate analyses by Poisson regression were used to identify associated factors.Results:The incidence of hyperglycemia in pregnancy was 14.9% (150/1,008), and 94.7% of these cases were gestational diabetes mellitus (142/150). Significant associated factors included a family history of diabetes mellitus, maternal overweight or obesity at enrollment, and previous maternal conditions (polycystic ovarian syndrome, thyroid dysfunctions and hypertensive disorders). A BMI 26.3Kg/m2(RRadj 1.87 [1.66–2.10]) and a family history of diabetes mellitus (RRadj 1.71 [1.37–2.15]) at enrollment were independent risk factors for HIP.Conclusions: A family history of diabetes mellitus and overweight or obesity (until 19–21 weeks of gestation) may be used as selective markers for HIP in Brazilian nulliparous women. Given the carcity of results in nulliparous women, our findings may contribute to determine the optimal diagnostic approach in populations of similar socioeconomic characteristics.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIA
local.publisher.initialsUFMG
local.url.externahttps://pubmed.ncbi.nlm.nih.gov/32401767/

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