Synthesis and phytotoxic profile of a new tetraoxane designed from a commercial auxin

dc.creatorIsabel V. Antolínez
dc.creatorLuiz Cláudio de Almeida Barbosa
dc.creatorCélia Maltha
dc.creatorGustavo Pereira
dc.creatorAntônio Silva
dc.date.accessioned2023-10-09T23:08:26Z
dc.date.accessioned2025-09-08T23:11:18Z
dc.date.available2023-10-09T23:08:26Z
dc.date.issued2020
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.21577/0100-4042.20170549
dc.identifier.issn0100-4042
dc.identifier.urihttps://hdl.handle.net/1843/59330
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofQuímica Nova
dc.rightsAcesso Aberto
dc.subjectHerbicidas
dc.subjectPeróxidos
dc.subject.otherWeed control
dc.subject.other2-(naphthalen-1-yl)acetic acid
dc.subject.otherTetraoxane
dc.subject.otherNew herbicide design
dc.subject.otherOrganic peroxide
dc.titleSynthesis and phytotoxic profile of a new tetraoxane designed from a commercial auxin
dc.typeArtigo de periódico
local.citation.epage908
local.citation.issue7
local.citation.spage901
local.citation.volume43
local.description.resumoModern agriculture relies on the massive use of agrochemicals, including herbicides. Despite their effectiveness, a continuous use of herbicides sharing the same target has resulted in the selection of weed biotypes resistant to such chemicals. To cope with this problem, the development of new herbicides is an urgent requirement. In this work we applied the Active compound Derivatization Method (ADM) strategy to develop a new tetraoxane (5), derived from the synthetic auxin 2-(naphtalen-1-yl)acetic acid (NAA). Greenhouse bioassays showed that 5 caused chlorosis, necrosis and leaf epinasty in Cucumis sativa. Furthermore, this compound, at the concentration of 1.25 x 10-5 mol L-1, inhibited the growth of important weeds such as Bidens pilosa, Iponomea acuminate, Solanum americanum and Althernantera ficoidea. For some weeds, the compound effect was higher or comparable to those caused by commercial glyphosate and imazethapyr. In addition, degradation studies revealed that 5 is transformed into NAA. The results also showed that 5 could act as photosynthesis inhibitor and as an auxin herbicide. In summary, we have discovered a new compound that may be a useful lead for the development of a commercial herbicide.
local.identifier.orcidhttps://orcid.org/0000-0002-5395-9608
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/qn/a/t6YsGpc78HSvSXM58bR664L/

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