Diversity and antimicrobial activity of culturable endophytic fungi associated with the neotropical ethnomedicinal plants Copaifera langsdorffii and Copaifera pubiflora
| dc.creator | Camila Rodriguesde Carvalho | |
| dc.creator | Mara Quintela Maia | |
| dc.creator | Marcos Sobral | |
| dc.creator | Gilmara Maria Duarte Pereira | |
| dc.creator | Krisle da Silva | |
| dc.creator | Marcos José Salgado Vital | |
| dc.creator | Jerri Édson Zilli | |
| dc.creator | Carlos Augusto Rosa | |
| dc.creator | Luiz Henrique Rosa | |
| dc.date.accessioned | 2024-08-07T21:26:11Z | |
| dc.date.accessioned | 2025-09-09T01:29:12Z | |
| dc.date.available | 2024-08-07T21:26:11Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | As plantas medicinais representam um reservatório promissor de diversos fungos endofíticos, incluindo táxons capazes de produzir metabólitos bioativos. No Brasil, o gênero Copaifera inclui espécies bem conhecidas na cultura popular medicina principalmente devido à sua capacidade de produzir oleorresina. Neste estudo caracterizamos as comunidades fúngicas endofíticas associadas a Copaifera langsdorffii e Copaifera pubiflora e investigamos sua capacidade de produzir agentes antimicrobianos. Obtivemos 668 isolados fúngicos de folhas, caules e sementes de ambos plantas, que posteriormente foram classificadas em 64 táxons e 22 gêneros. Diaporthe sp. 6, Xylariaceae sp. 1, Diaporthales sp. 1 e Diaporthales sp. 2 foram os táxons mais abundantes em C. langsdorffii, enquanto Phyllosticta sp., Diaporthe sp. 7, Diaporthales sp. 3, e Diaporthe miriciae foram os táxons mais abundantes em C. pubiflora. Diaporthe sp. 4, Phyllosticta sp., Diaporthe sp. 1, Diaporthe sp. 7 e Neopestalotiopsis sp. foram os únicos táxons comuns entre as duas plantas. Ambas as plantas apresentaram alta diversidade de fungos, especialmente C. langsdorffii. Seis extratos apresentaram propriedades antibacterianas, sendo Alternaria sp., Diaporthe sp. 1, D. miriciae e Diaporthe sp. 14. Nossos resultados mostraram que diferentes tecidos das plantas etnomedicinais C. langsdorffii e C. pubiflora são sistematicamente colonizados por comunidades fúngicas endofíticas ricas e diversas, e que alguns dos fungos são capazes de produzir compostos antimicrobianos, que podem ser explorados em estudos futuros como potenciais candidatos para o desenvolvimento de novas drogas. | |
| dc.format.mimetype | ||
| dc.identifier.doi | https://doi.org/10.1016/j.sajb.2021.06.021 | |
| dc.identifier.issn | 02546299 | |
| dc.identifier.uri | https://hdl.handle.net/1843/73321 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.relation.ispartof | South African Journal of Botany | |
| dc.rights | Acesso Aberto | |
| dc.subject | Microbima | |
| dc.subject | Endófitos | |
| dc.subject | Fungos | |
| dc.subject | Taxonomia | |
| dc.subject.other | Microbiota | |
| dc.subject.other | Endophytes | |
| dc.subject.other | Fungi | |
| dc.subject.other | Taxonomy | |
| dc.title | Diversity and antimicrobial activity of culturable endophytic fungi associated with the neotropical ethnomedicinal plants Copaifera langsdorffii and Copaifera pubiflora | |
| dc.title.alternative | Diversidade e atividade antimicrobiana de fungos endofíticos cultiváveis associada às plantas etnomedicinais neotropicais Copaifera langsdorffii e Copaifera pubiflora | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 315 | |
| local.citation.spage | 305 | |
| local.citation.volume | 142 | |
| local.description.resumo | Medicinal plants represent a promising reservoir of diverse endophytic fungi, including taxa that are able to produce bioactive metabolites. In Brazil, the genus Copaifera includes species that are well known in folk medicine mainly due to their ability to produce oleoresin. In this study, we characterized the endophytic fungal communities associated with Copaifera langsdorffii and Copaifera pubiflora and investigated their ability to produce antimicrobial agents. We obtained 668 fungal isolates from the leaves, stems, and seeds of both plants, which were later classified into 64 taxa and 22 genera. Diaporthe sp. 6, Xylariaceae sp. 1, Diaporthales sp. 1, and Diaporthales sp. 2 were the most abundant taxa in C. langsdorffii, while Phyllosticta sp., Diaporthe sp. 7, Diaporthales sp. 3, and Diaporthe miriciae were the most abundant taxa in C. pubiflora. Diaporthe sp. 4, Phyllosticta sp., Diaporthe sp. 1, Diaporthe sp. 7, and Neopestalotiopsis sp. were the only taxa common between the two plants. Both plants were found to have high fungal diversity, especially C. langsdorffii. Six extracts displayed antibacterial, being Alternaria sp., Diaporthe sp. 1, D. miriciae, and Diaporthe sp. 14. Our results showed that different tissues of the ethnomedicinal plants C. langsdorffii and C. pubiflora are systematically colonized by rich and diverse endophytic fungal communities, and that some of the fungi are able to produce antimicrobial compounds, which may be explored in further studies as potential candidates for the development of new drugs. | |
| local.publisher.country | Brasil | |
| local.publisher.department | ICB - DEPARTAMENTO DE BOTÂNICA | |
| local.publisher.initials | UFMG | |
| local.url.externa | https://www.sciencedirect.com/science/article/pii/S0254629921002362 |