Polymorphism of the beta-casein gene in holstein-zebu cows in the north of Minas Gerais, Brazil

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dc.creatorGeziella Aurea Aparecida Damasceno Souza
dc.creatorAlessandra Rejane Ericsson de Oliveira
dc.creatorAnna Christina de Almeida
dc.creatorMauro Aparecido de Sousa Xavier
dc.date.accessioned2025-07-08T11:40:52Z
dc.date.accessioned2025-09-09T00:51:31Z
dc.date.available2025-07-08T11:40:52Z
dc.date.issued2024
dc.identifier.doihttps://doi.org/10.29367/tv7af190
dc.identifier.issn1809-3957
dc.identifier.urihttps://hdl.handle.net/1843/83391
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofSodebras
dc.rightsAcesso Aberto
dc.subjectBovino de leite
dc.subjectBovino de leite -- Desempenho
dc.subjectReação em cadeia de polimerase
dc.subjectLeite -- Produção
dc.subject.otherBovino de leite
dc.subject.otherBovino de leite -- Desempenho
dc.subject.otherReação em cadeia de polimerase
dc.subject.otherLeite -- Produção
dc.titlePolymorphism of the beta-casein gene in holstein-zebu cows in the north of Minas Gerais, Brazil
dc.typeArtigo de periódico
local.citation.epage9
local.citation.issue221
local.citation.spage1
local.citation.volume19
local.description.resumoThis study aimed to investigate A1 and A2 polymorphisms of the beta-casein gene in crossbred Holstein-Zebu (HZ) cows from four herds in Northern Minas Gerais, Brazil. Blood samples were collected from 112 randomly selected cows, of wich 66 were at ½ HZ, and 46 were at ¾ HZ. DNA extraction was conducted using the phenol-chloroform method, and polymorphisms were evaluated using the amplification refractory mutation system - polymerase chain reaction technique. The results demonstrated that 72/112 (64.3%) cows were heterozygous (A1A2), 33/112 (29.5%) were homozygous for A2A2, and 7/112 (6.2%) were A1A1 homozygous. The percentage of A2A2 cows ranged from 10.7 to 41.4% among the evaluated herds. The frequencies of the A1 and A2 alleles were 38.4 and 61.6%, respectively. The A2 allele was the most frequent in both breeds. The ½ HZ cows were 1.8 times more likely (Odds Ratio) to belong to the A1A1 genotype. The distribution of genotypes was in Hardy-Weinberg equilibrium in three of the herds; however, the total of samples and the stratified samples according to breeds were not in equilibrium considering α = 0.05.
local.publisher.countryBrasil
local.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
local.publisher.initialsUFMG
local.url.externahttps://revista.sodebras.com.br/index.php/revista/article/view/31

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