Antimicrobial activity, effects on streptococcus mutans biofilm and interfacial bonding of adhesive systems with and without antibacterial agent

dc.creatorCarolina Bosso André
dc.creatorBrenda Paula Figueiredo Almeida Gomes
dc.creatorThais Mageste Duque
dc.creatorPedro Luiz Rosalen
dc.creatorDaniel Chi Ngai Chan
dc.creatorGlaucia Maria Bovi Ambrosano
dc.creatorMarcelo Giannini
dc.date.accessioned2022-08-29T18:06:58Z
dc.date.accessioned2025-09-08T23:52:37Z
dc.date.available2022-08-29T18:06:58Z
dc.date.issued2017-01
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format.mimetypepdf
dc.identifier.doi10.1016/j.ijadhadh.2016.10.011
dc.identifier.issn01437496
dc.identifier.urihttps://hdl.handle.net/1843/44674
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Adhesion and Adhesives
dc.rightsAcesso Restrito
dc.subjectAnti-infective agents
dc.subjectDentin-bonding agents
dc.subjectBiofilms
dc.subjectStreptococcus mutans
dc.subject.otherAntibacterial adhesives
dc.subject.otherDentine
dc.subject.otherHybrid layer
dc.titleAntimicrobial activity, effects on streptococcus mutans biofilm and interfacial bonding of adhesive systems with and without antibacterial agent
dc.typeArtigo de periódico
local.citation.epage129
local.citation.spage123
local.citation.volume72
local.description.resumoObjectives This study evaluated the antimicrobial activity (by agar disk diffusion test, AD), viability of S. mutans biofilm (VB), and effect on resin-dentin interface (RDI) of six adhesive systems. Methods Three adhesives containing antibacterial components (Gluma 2Bond (G2B)/glutaraldehyde, Clearfil SE Protect (CSP)/MDPB and Peak Universal Bond (PUB)/chlorhexidine) and the corresponding adhesives with similar composition, but without antibacterial agents (Gluma Comfort Bond, GCB; Clearfil SE Bond, CSB and Peak LC Bond, PLB) were evaluated. AD was determined measuring the extent of halo formation following application of adhesives and control groups (light cured or not) to cultures of four strict anaerobic and four facultative bacteria. For VB, a UA159 biofilm was grown on adhesive-coated hydroxyapatite discs for five days, collected and processed to count the number of viable cells. For RDI analysis, adhesives were applied according to manufacturers' recommendations and teeth were restored with resin composite, sectioned to obtain bonded slices and visualized by SEM. Results An inhibition halo was observed for G2B (strict anaerobic/light cured and not light cured), CSP (strict anaerobic and facultative/light cured and not light cured) and PUB (strict anaerobic and facultative/not light cured). PUB when light cured produced an inhibition halo on L. casei and S. mutans only. G2B and CSP significantly reduced the viability of S. mutans. Adhesives containing antimicrobial compounds had no detectable effect on RDI. Conclusion The MDPB-containing bonding agent showed better results of inhibition for all oral pathogens tested and a decrease of viability of Streptococcus mutans biofilm, among the adhesives tested
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S014374961630207X

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