A new trick for a conserved enzyme: mevalonate kinase, a glycosomal enzyme, can be secreted by Trypanosoma cruzi and modulate cell invasion and signaling. Is it another moonlighting enzyme?
| dc.creator | Diana Bahia | |
| dc.date.accessioned | 2021-08-03T11:58:55Z | |
| dc.date.accessioned | 2025-09-08T23:03:31Z | |
| dc.date.available | 2021-08-03T11:58:55Z | |
| dc.date.issued | 2017-09 | |
| dc.description.sponsorship | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico | |
| dc.description.sponsorship | FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais | |
| dc.identifier.doi | https://doi.org/10.3389/fcimb.2017.00426 | |
| dc.identifier.issn | 22352988 | |
| dc.identifier.uri | https://hdl.handle.net/1843/37201 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.relation.ispartof | Frontiers in cellular and infection microbiology | |
| dc.rights | Acesso Aberto | |
| dc.subject | Proteínas | |
| dc.subject | Trypanosoma cruzi | |
| dc.subject | Enzimas | |
| dc.subject.other | Moonlighting protein | |
| dc.subject.other | Mevalonate kinase | |
| dc.subject.other | Trypanosoma cruzi | |
| dc.subject.other | Invasion | |
| dc.subject.other | Signaling | |
| dc.title | A new trick for a conserved enzyme: mevalonate kinase, a glycosomal enzyme, can be secreted by Trypanosoma cruzi and modulate cell invasion and signaling. Is it another moonlighting enzyme? | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 5 | |
| local.citation.spage | 1 | |
| local.citation.volume | 7 | |
| local.description.resumo | “Moonlighting” means doing a second job, often at night, to earn more money. So-called moonlighting proteins are proteins that play other, generally unusual and unexpected, roles in addition to their canonical roles. They have been described in a wide range of organisms from bacteria to mammals, and their additional functions vary greatly (reviewed in Collingridge et al., 2010; Huberts and van der Klei, 2010; Henderson and Martin, 2011). | |
| local.publisher.country | Brasil | |
| local.publisher.department | ICB - DEPARTAMENTO DE BIOLOGIA GERAL | |
| local.publisher.initials | UFMG |