Effects of different radiation doses on the microhardness, superficial morphology, and mineral components of human enamel

dc.creatorSandra Ribeiro de Barros da Cunha
dc.creatorFelipe Paiva Fonseca
dc.creatorPedro Augusto Minorin Mendes Ramos
dc.creatorCecília Maria Kalil Haddad
dc.creatorEduardo Rodrigues Fregnani
dc.creatorAna Cecília Corrêa Aranha
dc.date.accessioned2023-09-28T18:57:02Z
dc.date.accessioned2025-09-09T00:48:28Z
dc.date.available2023-09-28T18:57:02Z
dc.date.issued2017-08
dc.identifier.doihttps://doi.org/10.1016/j.archoralbio.2017.04.007
dc.identifier.issn00039969
dc.identifier.urihttps://hdl.handle.net/1843/58998
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArchives of Oral Biology
dc.rightsAcesso Restrito
dc.subjectRadiotherapy
dc.subjectSpectrometry, X-Ray emission
dc.subjectDental enamel
dc.subjectHead and neck neoplasms
dc.subjectHardness
dc.subjectMinerals
dc.subjectMicroscopy, electron, scanning
dc.titleEffects of different radiation doses on the microhardness, superficial morphology, and mineral components of human enamel
dc.typeArtigo de periódico
local.citation.epage135
local.citation.spage130
local.citation.volume80
local.description.resumoObjective: To evaluate the effects of three different radiotherapy doses (20, 40, and 70Gy) on the microhardness, superficial morphology, and mineral content (based on Ca and P values) of three different depths of human enamel (cervical, middle, and occlusal). Design: Thirty-four third molars were cut, separated, and prepared. Microhardness samples (n=30) were embedded in acrylic resin and then polished, and depths were delimited. Microhardness tests were performed on cervical, middle, and occlusal enamel pre- and post-radiotherapy with a load of 50g for 30s. For the scanning electron microscopy (SEM) analysis (n=4) and energy dispersive X-ray spectroscopy (EDS) (n=12), samples were fixed in a 3% glutaraldehyde solution, washed in 0.1M cacodylate solution, and dehydrated in crescent concentrations of ethanol. Microhardness data were tested for significant differences using a two-way analysis of variance (ANOVA) and Tukey's test (p<0.05), while SEM and EDS were evaluated qualitatively. Results: The results showed a decrease in microhardness values only in the cervical enamel, regardless of the radiation dose used; no morphological or mineral change was observed. Conclusion: Radiotherapy can affect the microhardness values of only cervical enamel without compromising the morphological or mineral (Ca and P) content at any depth.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0003996917301176?via%3Dihub

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