Avaliação do impacto de um programa de atividade física na concentração plasmática de adipocitocinas e grelina em crianças obesas e com sobrepeso,de escolas públicas do município de Ouro Preto, MG

Abstract

The excess of fatty fabric is related to the risk of development of coronary arterial disease, systemic arterial hypertension, diabetes mellitus and dislipidemia, due to the action of the fatty as endocrine organ, through substances as adiponectin and leptin, that act in the metabolism and control of several systems. Aim: Analise the impact of intervention program of physical activity on the adiponectin, leptin and ghrelin plasma levels. Methods: A randomized controlled trial, double blind, with scholars from 6 to 9 years, caracterized overweight and obesity, from public schools of Ouro Preto city. 79 children were randomized to two groups (controls and intervention) and submitted at the x physical activity program, 3 times a week for 4 months. Were appraised levels of adiponectin, leptin, ghrelin, body mass index, percentile of fat, anthropometry, lipids profile and glicemy. To compare averages or medium among the groups, were applied parametric or no parametric tests. The impact of the program on the adiponectin, leptin and grelin levels was analyzed by two multivariate regression models (Best Subset and Stepwise Backward). Result: The characteristics of two groups were: 7,69 ±1,08 year-old and IMC of 19,87 ± 1,81 Kg.m2 for the control group and 7,09 ±1,12 year-old and IMC of 22,3 ±3,17 Kg.m2 for the intervention group. The explanations of the models were not above 80% for the two groups. Were observed statistical differenties between groups after intervention program to adiponectin levels (p=0,002), demonstrating an increase of individuals' proportion with larger levels of adiponectin in the intervention group and a decrease of body mass index and percentage of fat in this group. Conclusion: The impact of the intervention program was positive to increase adiponectin levels associated with a decrease of body mass index and percentage of fat. However, the models for those variables presented a low explanatory power in the adjusted models.