Full recovery from o'donoghue's triad with autologous bone marrow aspirate matrix: a case report

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dc.creatorJosé Fábio Santos Duartelana
dc.creatorAndré Atsushi Sugano
dc.creatorHenrique Valadão de Barros
dc.creatorTomas Mosaner
dc.creatorGabriel Silva Santos
dc.creatorJoão Vitor Bizinotto Lana
dc.creatorRodrigo Vicente
dc.creatorMarco Antônio Percope de Andrade
dc.date.accessioned2024-07-16T14:50:51Z
dc.date.accessioned2025-09-09T01:28:07Z
dc.date.available2024-07-16T14:50:51Z
dc.date.issued2022-11-11
dc.format.mimetypepdf
dc.identifier.doi10.3390/jfmk7040100
dc.identifier.issn2411-5142
dc.identifier.urihttps://hdl.handle.net/1843/70708
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Functional Morphology and Kinesiology
dc.rightsAcesso Aberto
dc.subjectTraumatismos do Joelho
dc.subjectLigamento Cruzado Anterior
dc.subjectMedula Óssea
dc.subjectMedicina Regenerativa
dc.titleFull recovery from o'donoghue's triad with autologous bone marrow aspirate matrix: a case report
dc.typeArtigo de periódico
local.citation.epage10
local.citation.issue4
local.citation.spage1
local.citation.volume7
local.description.resumoO’Donoghue’s triad is an extremely debilitating condition. Although there are many conventional treatments available, there is still no consensus regarding the most effective rehabilitation protocol for a full recovery. Surgical interventions have become an ordinary consideration, but problems may still persist even after the surgical procedure. Orthobiologics, however, have gained considerable popularity in regenerative medicine. Notable autologous alternatives, such as bone marrow aspirate (BMA), are often utilized in clinical settings. To our knowledge, the administration of BMA products for the management of O’Donoghue’s triad has not been thoroughly investigated in the literature. In this case report we describe a full recovery from O’Donoghue’s triad with BMA matrix in a patient who was recalcitrant to surgical intervention due to fear of complications. Our patient received three BMA matrix injections with four-week intervals, exhibiting significant recovery according to pain scores, functional assessment outcomes, and magnetic resonance imaging (MRI) results. The patient returned to normal activities with no complaints and MRI evidence at follow-up showed significant signs of structural restoration of the musculoskeletal tissues. Here, we demonstrate that autologous BMA products are a feasible alternative for the accelerated recovery of musculoskeletal tissue injury with safety and efficacy.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTOR
local.publisher.initialsUFMG
local.url.externahttps://www.mdpi.com/2411-5142/7/4/100

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