Melanotic neuroectodermal tumour of infancy of the jaws: an analysis of diagnostic features and treatment

Página do item simplificado
dc.creatorBruno Ramos Chrcanovic
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2025-01-27T17:08:15Z
dc.date.accessioned2025-09-08T23:42:55Z
dc.date.available2025-01-27T17:08:15Z
dc.date.issued2019-01
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.ijom.2018.08.006
dc.identifier.issn1399-0020
dc.identifier.urihttps://hdl.handle.net/1843/79498
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgery
dc.rightsAcesso Restrito
dc.subjectNeoplasms
dc.subjectMaxilla
dc.subjectTooth Avulsion
dc.subjectNeuroectodermal Tumor
dc.subjectMelanotic
dc.subjectOsteotomy
dc.subject.otherClinical features
dc.subject.otherMelanotic neuroectodermal tumour of infancy
dc.subject.otherRecurrence rate
dc.titleMelanotic neuroectodermal tumour of infancy of the jaws: an analysis of diagnostic features and treatment
dc.typeArtigo de periódico
local.citation.epage8
local.citation.issue1
local.citation.spage1
local.citation.volume48
local.description.resumoThe purpose of this study was to integrate the available published data on melanotic neuroectodermal tumour of infancy (MNTI) of the jaws into a comprehensive analysis of its clinical/radiological features, with emphasis on the predictive factors associated with recurrence. Eligibility criteria included publications with sufficient clinical/radiological/histological information to confirm the diagnosis. A total of 288 publications reporting 429 MNTI cases were included. MNTIs were slightly more prevalent in males and markedly more prevalent in the maxilla. Most of the lesions were asymptomatic, presenting cortical bone perforation and tooth displacement. Nine lesions were malignant, with metastasis in five cases. Enucleation was the predominant treatment (67.2%), followed by marginal (18.4%) and segmental resection (6.1%). Eighty-one of 356 lesions (22.8%) recurred. Recurrence rates were 61.5% for curettage, 25.3% for enucleation alone, 16.2% for enucleation+curettage, 20.0% for enucleation+peripheral osteotomy, 11.3% for marginal resection, 10.0% for segmental resection, 30.0% for chemotherapy, and 33.3% for radiotherapy. Enucleation and resection presented significantly lower recurrence rates in comparison to curettage. Curettage appears not to be the best form of treatment, due to its high recurrence rate. As resection (either marginal or segmental) is associated with higher morbidity, enucleation with or without complementary treatment (curettage or peripheral osteotomy) would appear to be the most indicated therapy.
local.identifier.orcidhttps://orcid.org/0000-0002-3460-3374
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.ijoms.com/article/S0901-5027(18)30323-0/abstract

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG