Energy expenditure and liver transplantation: what We know and where We are

dc.creatorBárbara Chaves Santos
dc.creatorMaria Isabel Toulson Davisson Correia
dc.creatorLucilene Rezende Anastácio
dc.date.accessioned2022-04-04T23:01:33Z
dc.date.accessioned2025-09-08T23:30:11Z
dc.date.available2022-04-04T23:01:33Z
dc.date.issued2020
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.format.mimetypepdf
dc.identifier.doi10.1002/jpen.1985
dc.identifier.issn0148-6071
dc.identifier.urihttps://hdl.handle.net/1843/40766
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Parenteral and Enteral Nutrition
dc.rightsAcesso Aberto
dc.subjectTransplante
dc.subjectFígado
dc.subject.otherEnergy expenditure
dc.subject.otherEnergy metabolism
dc.subject.otherIndirect calorimetry
dc.subject.otherLiver transplantation
dc.titleEnergy expenditure and liver transplantation: what We know and where We are
dc.typeArtigo de periódico
local.citation.epage464
local.citation.issue3
local.citation.spage456
local.citation.volume45
local.description.resumoPatients with end-stage liver disease (ESLD) and undergoing liver transplantation (LTx) commonly present with malnutrition attributed to various etiologies. One of the causes is potential hypermetabolism resulting from increased resting energy expenditure (REE). After the surgery, it is hypothesized that these patients show a reduction in REE, which may contribute to the weight gain observed in this population. However, there have been controversial results regarding the metabolic status of ESLD patients and liver recipients, which has led us to critically review the pertinent literature. We enrolled studies with the following goals: assessment of REE of these patients either before or after surgery by using indirect calorimetry (measured REE [mREE]) and comparison of these mREE values with those of healthy controls or with REE values obtained using predictive equations (predicted REE [pREE]). For most patients, mREE and pREE values were comparable. However, ≥5.3% of patients exhibited hypermetabolism when the mREE was compared with the pREE using the Harris-Benedict formula. Three follow-up studies that were conducted postsurgery showed a progressive reduction in the mREE for ≤1 year. However, conflicting data have been published, and cross-sectional studies have not reported hypometabolic patients. In conclusion, there is no consensus regarding the metabolic status of pre-LTx and post-LTx patients, which may be due to differences in the methods used for comparison. Therefore, we highlight this aspect of LTx patient management, which impacts the quality of nutrition therapy required by these patients.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://aspenjournals.onlinelibrary.wiley.com/doi/10.1002/jpen.1985

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