Might anxiety disorders promote head and neck cancer development?

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dc.creatorMarcela Gonçalvesde Souza
dc.creatorEmisael Stênio Batista Gomes
dc.creatorLorena Barbosa Costa
dc.creatorAmanda Dias Silva Andrade
dc.creatorSabrina Ferreira de Jesus
dc.creatorDaniela Paola Santos de Paula
dc.creatorRogério Gonçalves da Rocha
dc.creatorSérgio Henrique Sousa Santos
dc.creatorAlfredo Maurício Batista de Paula
dc.creatorLucyana Conceição Farias
dc.creatorAndré Luiz Sena Guimarães
dc.date.accessioned2022-09-06T14:09:10Z
dc.date.accessioned2025-09-08T22:54:33Z
dc.date.available2022-09-06T14:09:10Z
dc.date.issued2020-12
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doihttps://doi.org/10.1016/j.ibror.2020.06.001
dc.identifier.issn2451-8301
dc.identifier.urihttps://hdl.handle.net/1843/44946
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofIBRO Reports
dc.rightsAcesso Aberto
dc.subjectTranstornos da ansiedade
dc.subjectCabeça - Câncer
dc.subjectPescoço - Câncer
dc.subjectCarcinoma de células escamosas
dc.subjectTumores
dc.titleMight anxiety disorders promote head and neck cancer development?
dc.typeArtigo de periódico
local.citation.epage13
local.citation.spage9
local.citation.volume9
local.description.resumoCancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma.
local.publisher.countryBrasil
local.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2451830120300169

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