Cost-effectiveness analysis of diagnostic-therapeutic strategies for visceral leishmaniasis in Brazil

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dc.creatorTália Santana Machado Assis
dc.creatorAna Rabello
dc.creatorGlaucia Fernandes Cota
dc.creatorGuilherme Loureiro Werneck
dc.creatorAndré Luís Ferreira de Azeredo-da-Silva
dc.date.accessioned2024-12-06T11:09:37Z
dc.date.accessioned2025-09-09T00:50:26Z
dc.date.available2024-12-06T11:09:37Z
dc.date.issued2019
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipOutra Agência
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0272-2018
dc.identifier.issn1678-9849
dc.identifier.urihttps://hdl.handle.net/1843/78489
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical / Journal of the Brazilian Society of Tropical Medicine
dc.rightsAcesso Aberto
dc.subjectLeishmaniose Visceral
dc.subjectAnálise de Custo-Efetividade
dc.subjectDiagnóstico
dc.titleCost-effectiveness analysis of diagnostic-therapeutic strategies for visceral leishmaniasis in Brazil
dc.typeArtigo de periódico
local.citation.epage5
local.citation.spage1
local.citation.volume52
local.description.resumoINTRODUCTION: Visceral leishmaniasis (VL) is fatal if not diagnosed and treated. This study aimed to estimate the cost-effectiveness of diagnostic-therapeutic alternatives for VL in Brazil. METHODS: A decision model estimated the life expectancy and costs of six diagnostic-therapeutic strategies. RESULTS: IT LEISH + liposomal amphotericin B emerged the best option, presenting lower costs and higher effectiveness. DAT-LPC + liposomal amphotericin B showed an incremental cost-effectiveness ratio of US$ 326.31 per life year. CONCLUSIONS: These findings indicate the feasibility of incorporating DAT and designating liposomal amphotericin B as the first-line drug for VL in Brazil.
local.publisher.countryBrasil
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/rsbmt/a/rNfctRtsf8rTYMypVKmJPYc/#

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