Non-pharmacologic strategies for the management of intestinal inflammation

dc.creatorTatiani Uceli Maioli
dc.creatorLuísa Martins Trindade
dc.creatorAline Souza
dc.creatorLícia Torres
dc.creatorMaria Emília Rabelo Andrade
dc.creatorValbert Nascimento Cardoso
dc.creatorSimone de Vasconcelos Generoso
dc.date.accessioned2024-03-19T14:33:50Z
dc.date.accessioned2025-09-08T22:50:03Z
dc.date.available2024-03-19T14:33:50Z
dc.date.issued2022
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.identifier.doihttps://doi.org/10.1016/j.biopha.2021.112414
dc.identifier.issn1950-6007
dc.identifier.urihttps://hdl.handle.net/1843/66060
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBiomedicine & Pharmacotherapy
dc.rightsAcesso Aberto
dc.subjectDoenças inflamatórias intestinais
dc.subjectÁcidos graxos Ômega-3
dc.subjectProbióticos
dc.subjectPrebióticos
dc.subjectSimbióticos
dc.subjectDieta FODMAP
dc.subject.otherIntestinal inflammation
dc.subject.otherOmega-3
dc.subject.otherProbiotic
dc.subject.otherPrebiotic
dc.subject.otherSynbiotic
dc.subject.otherFODMAP
dc.titleNon-pharmacologic strategies for the management of intestinal inflammation
dc.typeArtigo de periódico
local.citation.volume145
local.description.resumoInflammatory bowel diseases, irritable bowel syndrome, and mucositis are characterized by intestinal inflammation, but vary according to their pathological mechanisms, severity, location, and etiology. Significant intestinal inflammation that occurs in these diseases induces weight loss, nutritional depletion, and gastrointestinal tract dysfunction. Nutritional support is important in alleviating symptoms and improving patients’ quality of life. In this review, we summarize some nutritional components used to manage intestinal disorders. These include fatty acids, probiotics, parabiotics, postbiotics, prebiotics, synbiotics, and low FODMAP (LFD) diets. These components and LFD diets have been studied and clinical trials have been designed to develop new strategies to alleviate intestinal inflammation and improve the quality of life. Clinical trials on their use in intestinal inflammation do not allow firm conclusions to be drawn mainly because of the heterogeneity of the dose used and the study design or their inconclusive results. However, in the majority of cases, the use of omega-3, probiotics, parabiotics, postbiotics, prebiotics, synbiotics, and LFD improve the health.
local.identifier.orcidhttps://orcid.org/0000-0002-7538-3208
local.identifier.orcidhttps://orcid.org/0000-0001-7597-9602
local.identifier.orcidhttps://orcid.org/0000-0001-6413-8031
local.publisher.countryBrasil
local.publisher.departmentENF - DEPARTAMENTO DE NUTRIÇÃO
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0753332221012002?via%3Dihub

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