Differences in spontaneous speech fluency between parkinson's disease and spinocerebellar ataxia type 3

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dc.creatorVanessa Brzoskowskidos Santos
dc.creatorRui Rothe-Neves
dc.creatorMaira Rozenfeld Olchik
dc.creatorAnnelise Ayres
dc.creatorMaiara Laís Mallmann Kieling
dc.creatorElaine Cristina Miglorini
dc.creatorLaura Bannach Jardim
dc.creatorArtur Francisco Schumacher-Schuh
dc.creatorCarlos Roberto de Mello Rieder
dc.creatorRaphael Machado de Castilhos
dc.creatorKristie Spencer
dc.date.accessioned2024-12-16T13:21:20Z
dc.date.accessioned2025-09-08T23:56:28Z
dc.date.available2024-12-16T13:21:20Z
dc.date.issued2023-05-05
dc.format.mimetypepdf
dc.identifier.doi10.3389/fneur.2023.1179287
dc.identifier.issn1664-2295
dc.identifier.urihttps://hdl.handle.net/1843/78694
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofFrontiers in Neurology
dc.rightsAcesso Aberto
dc.subjectLinguística
dc.subjectParkinson, Doença de
dc.subjectDistúrbios da fala
dc.subject.otherParkinson's disease
dc.subject.otherSpinocerebellar ataxia
dc.subject.otherSpeech disorders
dc.subject.otherDysarthria
dc.subject.otherArticulation disorders
dc.titleDifferences in spontaneous speech fluency between parkinson's disease and spinocerebellar ataxia type 3
dc.typeArtigo de periódico
local.citation.epage06
local.citation.spage01
local.citation.volume14
local.description.resumoBackground: The basal ganglia and cerebellum both have a role in speech production although the effect of isolated involvement of these structures on speech fluency remains unclear. Objective: The study aimed to assess the differences in the articulatory pattern in patients with cerebellar vs. basal ganglia disorders. Methods: A total of 20 individuals with Parkinson's disease (PD), 20 with spinocerebellar ataxia type 3 (SCA3), and 40 controls (control group, CG) were included. Diadochokinesis (DDK) and monolog tasks were collected. Results: The only variable that distinguished SCA3 carriers from the CG was the number of syllables in the monolog, with SCA3 patients of a significantly lower number. For patients with PD, the number of syllables, phonation time, DDK, and monolog were significantly lower than for CG. Patients with PD were significantly worse compared to patients with SCA3 in the number of syllables and phonation time in DDK, and phonation time in monolog. Additionally, there was a significant correlation between the number of syllables in the monolog and the MDS-UPDRS III for participants with PD, and the Friedreich Ataxia Rating Scale for participants with SCA3 suggesting a relationship between speech and general motor functioning. Conclusion: The monolog task is better at discriminating individuals with cerebellar vs. Parkinson's diseases as well as differentiating healthy control and was related to the severity of the disease.Background: The basal ganglia and cerebellum both have a role in speech production although the effect of isolated involvement of these structures on speech fluency remains unclear. Objective: The study aimed to assess the differences in the articulatory pattern in patients with cerebellar vs. basal ganglia disorders. Methods: A total of 20 individuals with Parkinson's disease (PD), 20 with spinocerebellar ataxia type 3 (SCA3), and 40 controls (control group, CG) were included. Diadochokinesis (DDK) and monolog tasks were collected. Results: The only variable that distinguished SCA3 carriers from the CG was the number of syllables in the monolog, with SCA3 patients of a significantly lower number. For patients with PD, the number of syllables, phonation time, DDK, and monolog were significantly lower than for CG. Patients with PD were significantly worse compared to patients with SCA3 in the number of syllables and phonation time in DDK, and phonation time in monolog. Additionally, there was a significant correlation between the number of syllables in the monolog and the MDS-UPDRS III for participants with PD, and the Friedreich Ataxia Rating Scale for participants with SCA3 suggesting a relationship between speech and general motor functioning. Conclusion: The monolog task is better at discriminating individuals with cerebellar vs. Parkinson's diseases as well as differentiating healthy control and was related to the severity of the disease.
local.identifier.orcidhttps://orcid.org/0000-0002-2322-3499
local.identifier.orcidhttps://orcid.org/0000-0003-3205-3660
local.identifier.orcidhttps://orcid.org/0000-0002-8732-9225
local.identifier.orcidhttps://orcid.org/0000-0003-3205-3660
local.identifier.orcidhttps://orcid.org/0000-0002-1110-3270
local.identifier.orcidhttps://orcid.org/0000-0001-6907-5068
local.identifier.orcidhttps://orcid.org/0000-0002-8722-0908
local.identifier.orcidhttps://orcid.org/0000-0003-2950-7211
local.identifier.orcidhttps://orcid.org/0000-0002-1905-2084
local.identifier.orcidhttps://orcid.org/0000-0003-4747-9293
local.identifier.orcidhttps://orcid.org/0000-0002-8896-8862
local.publisher.countryBrasil
local.publisher.departmentFALE - FACULDADE DE LETRAS
local.publisher.initialsUFMG
local.url.externahttps://www.frontiersin.org/articles/10.3389/fneur.2023.1179287/full

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