Uso de medicamentos que aumentam o risco de queda entre pacientes com osteoporose na pós-menopausa

Abstract

Objective: Drugs called Fall-Risk-Incrising Drugs (FRID) are associated with a higher risk of falls amongaged people. The present study evaluated the use of such drugs among aged patients with postmenopausal osteoporosis who attended to the “Mais vida” Program and the associated factors. Methods: A cross-sectional study was carried out using the medical records of aged women (age ≥ 60 years) with postmenopausal osteoporosis, with continuous use of at least one medication, included in the Program between September/2011 and December/2013 (n=478). FRIDs were identified and characterized as a dependent variable for the univariate and multivariate analysis (use of any FRIDs; use of any FRID of the cardiovascular therapeutic group; or use of any FRID of the central nervous system therapeutic group). Multiple independent variables were used in these analysis (age, number of health problems, number of medications, hypertension, depression, presence of cognitive deficit or dementia). Results: The prevalence of FRID use was 87.9% (95%CI 84.9-90.8). Hypertension was associated with the use of any FRID (OR=2.06; 95%CI 1.17-3.62), as well as the use of seven or more medications (OR=2.82; 95%CI 1.53-5.21). As for the central nervous system FRIDs, its use was associated with the use of seven or more medications (OR=2.06; 95%CI 1.41-3.00) and depression (OR=2.67; 95%CI 1.81-3.93). For the use of cardiovascular system FRID, the use of seven or more medications (OR = 2.04, 95% CI 1.34-3.09) and hypertension (OR = 3.65, 95% CI, 2.41-5.52) was associated. Conclusion: A high prevalence of FRID use was identified, reinforcing the need for greater attention to the choice of drugs for this population, to the pharmacotherapeutic follow-up process and to the development of fall prevention strategies, which can be guided by prioritizing the associated factors identified in the present study.