Use of pedicled and free buccal fat pad in medication-related osteonecrosis of the jaw treatment
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Universidade Federal de Minas Gerais
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Background: Management of medication related osteonecrosis of the jaw (MRONJ) remains a clinical challenge. Many treatment options are described, but each case should be treated individually, depending on clinical manifestations as well as patient's medical condition. Sequestrectomy and primary closure are usually employed, but surgical resections could be necessary. Pedicled buccal fat pad (PBFP) has been proposed to aid in soft tissue covering and healing, especially in posterior maxillary cases. However, free buccal fat pat (FBFP) use in MRONJ treatment has not been described.
Objectives: The objective of this study was to evaluate the use of pedicled and free buccal fat pad (BFP) in MRONJ treatment.
Methods: This study was previously approved by local ethical committee. Thirteen MRONJ patients were treated – 8 under osteoporosis treatment (Group 1) and five undergoing malignant neoplasm therapy (Group 2). All patients were submitted to sequestrectomy and primary closure using BFP. In Group 1, five patients were treated by means of PBFP and three with FBFP. In Group 2, four patients were treated with PBFP and one with FBFP. All PBFP treatment were in posterior maxillary region whereas FBFP were in mandible.
Findings: All cases achieved complete healing after 8 weeks of follow-up. PBFP had a higher volume maintenance in the treated sites comparing to FBFP.
Conclusion: The use of BFP in MRONJ treatment looks promising in both groups. Despite its apparent postoperative success in both forms, future prospective studies with a larger number of patients are necessary to prove these results.
Abstract
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Fat, Mouth, Evaluation study, Therapeutics, Pathology
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International journal of oral & maxillofacial surgery, acesso restrito Use of pedicled and free buccal fat pad in medication-related osteonecrosis of the jaw treatment fao clínica dia 16/07/2024 16 e 23 a hora
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https://www.ijoms.com/article/S0901-5027(19)30798-2/fulltext