Statin use in Brazil: findings and implications

dc.creatorRenata Cristina Rezende Macedo do Nascimento
dc.creatorAugusto Afonso Guerra Júnior
dc.creatorJuliana Álvares Teodoro
dc.creatorIsabel Cristina Gomes
dc.creatorBrian Godman
dc.creatorMarion Bennie
dc.creatorAmanj Baker Kurdi
dc.creatorFrancisco de Assis Acúrcio
dc.date.accessioned2025-08-04T20:08:05Z
dc.date.accessioned2025-09-08T23:47:51Z
dc.date.available2025-08-04T20:08:05Z
dc.date.issued2018-04-12
dc.format.mimetypepdf
dc.identifier.doi10.1080/03007995.2018.1451312
dc.identifier.issn03007995
dc.identifier.urihttps://hdl.handle.net/1843/84017
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.rightsAcesso Aberto
dc.subjectMedicamentos
dc.subjectDoenças cardiovasculares
dc.subject.otherBrasil
dc.subject.otherDoenças cardiovasculares
dc.subject.otherUtilização de medicamentos
dc.subject.otherHipercolesterolemia
dc.subject.otherServiços farmacêuticos
dc.subject.otherAtenção primária à saúde
dc.subject.otherEstatinas
dc.titleStatin use in Brazil: findings and implications
dc.typeArtigo de periódico
local.citation.epage9
local.citation.issue10
local.citation.spage1
local.citation.volume34
local.description.resumoIntroduction and objectives: Statins have become an integral part of treatment to reduce cardiac events in patients with cardiovascular disease. However, their use within the public healthcare system in Brazil is unknown. Consequently, we sought to determine and characterize statin use in primary healthcare delivered by the public health system (SUS) in Brazil and evaluate associated patient factors to improve future use. Methods: Cross-sectional study with a national representative sample from five Brazilian regions, derived from the National Survey on Access, Use and Promotion of Rational Use of Medicines using a multi-stage complex sampling plan. Patients over 18 years old were interviewed from July 2014 to May 2015. The prevalences of statin use and self-reported statin adherence were determined amongst medicine users. The associations between statin use and sociodemographic/health condition variables were assessed using logistic regression. Results: A total of 8803 patients were interviewed, of whom 6511 were medicine users. The prevalence of statin use was 9.4% with simvastatin (90.3%), atorvastatin (4.7%) and rosuvastatin (1.9%) being the most used statins. Poor adherence was described by 6.5% of patients. Statin use was significantly associated with age ≥65 years old, higher educational level, residence in the South, metabolic and heart diseases, alcohol consumption and polypharmacy. Conclusions: This is the first population based study in Brazil to assess statin use in SUS primary healthcare patients. Addressing inequalities in access and use of medicines including statins is an important step in achieving the full benefit of statins in Brazil, with the findings guiding future research and policies.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIAL
local.publisher.initialsUFMG
local.url.externahttps://strathprints.strath.ac.uk/63471/

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