Reference equation for maximal voluntary ventilation in children and adolescents

dc.creatorJaksoel Cunha Silva
dc.creatorIdeza Carvalho
dc.creatorSimone Dal Corso
dc.creatorFernanda de Córdoba Lanza
dc.date.accessioned2022-07-15T15:38:12Z
dc.date.accessioned2025-09-08T22:53:30Z
dc.date.available2022-07-15T15:38:12Z
dc.date.issued2020-02
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1002/ppul.24576
dc.identifier.issn1099-0496
dc.identifier.urihttps://hdl.handle.net/1843/43312
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofPediatric Pulmonology
dc.rightsAcesso Aberto
dc.subjectAdolescentes
dc.subjectCrianças
dc.subjectVentilação
dc.subjectReprodutibilidade dos testes
dc.subjectVentilação Voluntária Máxima (MVV)
dc.subject.otherAdolescents
dc.subject.otherChildren
dc.subject.otherMaximal voluntary
dc.subject.otherReference equation
dc.subject.otherVentilation
dc.titleReference equation for maximal voluntary ventilation in children and adolescents
dc.typeArtigo de periódico
local.citation.epage432
local.citation.issue2
local.citation.spage426
local.citation.volume55
local.description.resumoObjectives: To develop reference equations of maximal voluntary ventilation (MVV) in children and adolescents, and to test the validity and reproducibility of MVV. Study Design: Cross-sectional study. Patient-Subject selection: A total of 348 healthy volunteers (6-17 years)—248 for the development of reference equations and 100 to test the validity— were selected. Methodology: Spirometry and MVV were performed. Volunteers were instructed to breathe quickly and strongly to estimate the MVV. Independent variables tested were age, sex, weight, height, and pulmonary function. Results: All volunteers (50% boys) had a normal pulmonary function. Mean MVV was 66.3 (17.8) L/minute for children and 118.8 (20.0) L/minute for adolescents. The equation developed for children was MVV = 4.865 + (forced expiratory volume in the first second [FEV1] × 16.257) + (peak expiratory flow [PEF] × 7.621); for adolescents was MVV = −25.450 + (FEV1 × 11.591) + (PEF × 6.672) + (sex × 12.179) + (age × 3.613). No significant differences were observed between measured and predicted MVV in children (64.6 [10.3] vs 64.6 [8.5] L/minute; P = .34) or adolescents (111.8 [23.4] vs 113.1 [22.8] L/minute, P = .12). The intraclass correlation coefficient between measured and predicted MVV was 0.95 (0.91-0.97) for children and 0.90 (0.82-0.94) for adolescents. The mean bias of Bland-Altman analysis was −0.8 L/minute for children and −2.7 L/minute for adolescents. Conclusions: Normative values for MVV were established for children and adolescents, additionally, these equations are reproducible and it can be used to determine the respiratory impairments in the pediatric population.
local.identifier.orcidhttps://orcid.org/ 0000-0001-9190-6796
local.identifier.orcidhttps://orcid.org/0000-0002-4748-6947
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/full/10.1002/ppul.24576#:~:text=The%20equation%20developed%20for%20children,%2B%20(age%20%C3%97%203.613).

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