ABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores

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dc.creatorMilena S.marcolino
dc.creatorFernando Anschau
dc.creatorRoberta Pozza
dc.creatorRoberta x. Campos
dc.creatorRochele m. Menezes
dc.creatorRoger m. de Abreu
dc.creatorRufino de f. Silva
dc.creatorSilvana M.m. Guimarães
dc.creatorSilvia f. Araújo
dc.creatorSusany Anastácia Pereira
dc.creatorTalita f. Oliveira
dc.creatorJuliana m. Rugolo
dc.creatorKaren Cristina J.r. Pontes
dc.creatorKauane Aline m. Dos Santos
dc.creatorRodolfo Lucas s. Mourato
dc.creatorLeonardo s. de Oliveira
dc.creatorLílian s. Pinheiro
dc.creatorLiliane s. Pacheco
dc.creatorLucas de d. Sousa
dc.creatorLuciana S.f. Couto
dc.creatorLuciane Kopittke
dc.creatorMaria Aparecida c. Bicalho
dc.creatorLuis Cesar s. de Moura
dc.creatorLuisa Elem a. Santos
dc.creatorMáderson A.s. Cabral
dc.creatorMaíra d. Souza
dc.creatorAdrián Sánchez-montalvá
dc.creatorMarcela G.t. Tofani
dc.creatorMarcelo Carneiro
dc.creatorMaria Angélica p. Ferreira
dc.creatorMaria Clara P.b. Lima
dc.creatorMariana f. Godoy
dc.creatorMarilia M.a. Cardoso
dc.creatorMeire p. Figueiredo
dc.creatorNatália C.s. Sampaio
dc.creatorNatália l. Rangel
dc.creatorBerta Raventós
dc.creatorNatália t. Crespo
dc.creatorNeimy r. de Oliveira
dc.creatorTatiana Kurtz
dc.creatorPedro l. Assaf
dc.creatorPetrônio José de l. Martelli
dc.creatorRafaela S.c. Almeida
dc.creatorRaphael c. Martins
dc.creatorRaquel Lutkmeier
dc.creatorReginaldo Aparecido Valacio
dc.creatorRenan g. Finger
dc.creatorRicardo b. Cardoso
dc.creatorJosé Miguel Chatkin
dc.creatorThainara c. de Oliveira
dc.creatorThaíza Simônia M.a. Araújo
dc.creatorThulio Henrique o. Diniz
dc.creatorVeridiana b. Dos Santos
dc.creatorVirginia Mara r. Gomes
dc.creatorVitor Augusto l. do Vale
dc.creatorYuri c. Ramires
dc.creatorEric Boersma
dc.creatorCarisi a. Polanczyk
dc.creatorMatheus Carvalho Alves Nogueira
dc.creatorMilton h. Guimarães-júnior
dc.creatorGiovanna g. Vietta
dc.creatorHelena Duani
dc.creatorDaniela Ponce
dc.creatorPatricia k. Ziegelmann
dc.creatorLuís c. Castro
dc.creatorKaren b. Ruschel
dc.creatorChristiane C.r. Cimini
dc.creatorSaionara c. Francisco
dc.creatorMaiara a. Floriani
dc.creatorGuilherme f. Nascimento
dc.creatorBárbara l. Farace
dc.creatorLuanna s. Monteiro
dc.creatorMaira V.r. Souza-silva
dc.creatorThais L.s. Sales
dc.creatorKarina Paula M.p. Martins
dc.creatorIsrael j. Borges do Nascimento
dc.creatorLucas Emanuel f. Ramos
dc.creatorTatiani o. Fereguetti
dc.creatorDaniel T.m.o. Ferrara
dc.creatorFernando a. Botoni
dc.creatorAna Paula B.s. Etges
dc.creatorAlexandre v. Schwarzbold
dc.creatorAmanda o. Maurílio
dc.creatorAna Luiza B.a. Scotton
dc.creatorAndré p. Weber
dc.creatorAndré S.m. Costa
dc.creatorAndressa b. Glaeser
dc.creatorRafael t. Silva
dc.creatorAngélica Aparecida c. Madureira
dc.creatorAngelinda r. Bhering
dc.creatorBruno Mateus de Castro
dc.creatorCarla Thais C.a. da Silva
dc.creatorCarolina m. Ramos
dc.creatorCaroline d. Gomes
dc.creatorCíntia a. de Carvalho
dc.creatorDaniel v. Silveira
dc.creatorEdilson Cezar
dc.creatorMagda c. Pires
dc.creatorElayne c. Pereira
dc.creatorLuana m. Oliveira
dc.creatorEmanuele Marianne s. Kroger
dc.creatorFelipe b. Vallt
dc.creatorFernanda b. Lucas
dc.creatorFernando g. Aranha
dc.creatorFrederico Bartolazzi
dc.creatorGabriela p. Crestani
dc.creatorGisele A.n. Bastos
dc.creatorGlícia Cristina de c. Madeira
dc.creatorHelena Carolina Noal
dc.creatorHeloisa r. Vianna
dc.creatorRafael L.r. Carvalho
dc.creatorHenrique c. Guimarães
dc.creatorIsabela m. Gomes
dc.creatorIsrael Molina
dc.creatorJoanna D'arc l. Batista
dc.creatorJoice c. de Alvarenga
dc.creatorJúlia D.s.s. Guimarães
dc.creatorJúlia D.p. de Morais
dc.date.accessioned2023-08-07T18:39:23Z
dc.date.accessioned2025-09-09T01:17:52Z
dc.date.available2023-08-07T18:39:23Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2021.07.049
dc.identifier.issn1201-9712
dc.identifier.urihttps://hdl.handle.net/1843/57557
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Infectious Diseases
dc.rightsAcesso Aberto
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectMortalidade
dc.subjectPrognóstico
dc.subjectFatores de risco
dc.subjectHospitalizações
dc.subject.otherCOVID-19
dc.subject.otherSARS-CoV-2
dc.subject.otherMortality
dc.subject.otherPrognosis
dc.subject.otherRisk factors
dc.subject.otherHospitalizations
dc.titleABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores
dc.typeArtigo de periódico
local.citation.epage308
local.citation.spage281
local.citation.volume110
local.description.resumoObjectives: The majority of available scores to assess mortality risk of coronavirus disease 2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this cohort aimed to develop and validate a score at hospital admission for predicting in-hospital mortality in COVID-19 patients and to compare this score with other existing ones.Methods: Consecutive patients (≥ 18 years) with confirmed COVID-19 admitted to the participating hos pitals were included. Logistic regression analysis was performed to develop a prediction model for in hospital mortality, based on the 3978 patients admitted between March–July, 2020. The model was validated in the 1054 patients admitted during August–September, as well as in an external cohort of 474 Spanish patients.Results: Median (25–75th percentile) age of the model-derivation cohort was 60 (48–72) years, and in hospital mortality was 20.3%. The validation cohorts had similar age distribution and in-hospital mor tality. Seven significant variables were included in the risk score: age, blood urea nitrogen, number of comorbidities, C-reactive protein, SpO2/FiO2 ratio, platelet count, and heart rate. The model had high discriminatory value (AUROC 0.844, 95% CI 0.829–0.859), which was confirmed in the Brazilian (0.859 [95% CI 0.833–0.885]) and Spanish (0.894 [95% CI 0.870–0.919]) validation cohorts, and displayed better discrimination ability than other existing scores. It is implemented in a freely available online risk calculator (https://abc2sph.com/). Conclusions: An easy-to-use rapid scoring system based on characteristics of COVID-19 patients com monly available at hospital presentation was designed and validated for early stratification of in-hospital mortality risk of patients with COVID-19.
local.identifier.orcidhttps://orcid.org/0000-0001-9345-018X
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE ESTATÍSTICA
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1201971221006056?via%3Dihub

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