Effects of exercise training and CPAP in patients with heart failure and OSA: a preliminary study

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dc.creatorDenise Maria Servantes
dc.creatorShahrokh Javaheri
dc.creatorAna Claudia Pelissari Kravchychyn
dc.creatorLuciana Julio Storti Mancuso
dc.creatorDirceu Rodrigues de Almeida
dc.creatorMarco Túlio de Mello
dc.creatorFátima Dumas Cintra
dc.creatorSergio Tufik
dc.creatorLia Rita Azeredo Bittencourt
dc.date.accessioned2023-03-16T18:49:48Z
dc.date.accessioned2025-09-08T23:30:37Z
dc.date.available2023-03-16T18:49:48Z
dc.date.issued2018-10
dc.identifier.doihttps://doi.org/10.1016/j.chest.2018.05.011
dc.identifier.issn0012-3692
dc.identifier.urihttps://hdl.handle.net/1843/50962
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofChest
dc.rightsAcesso Restrito
dc.subjectPressão positiva contínua nas vias aéreas
dc.subjectExercícios físicos
dc.subjectInsuficiencia cardíaca
dc.subjectSíndromes da apnéia do sono
dc.subject.otherCPAP
dc.subject.otherExercise
dc.subject.otherHeart failure
dc.subject.otherSleep apnea
dc.titleEffects of exercise training and CPAP in patients with heart failure and OSA: a preliminary study
dc.typeArtigo de periódico
local.citation.epage817
local.citation.issue4
local.citation.spage808
local.citation.volume154
local.description.resumoBackground: Exercise and CPAP improve OSA. This study examined the effects of exercise in patients with heart failure (HF) and OSA. Methods: Patients with HF and OSA were randomized to the following study groups: control, exercise, CPAP, and exercise + CPAP. Results: Sixty-five participants completed the protocol. Comparing baseline vs 3 months, the mean apnea-hypopnea index (AHI) did not change significantly (in events per hour) in the control group, decreased moderately in the exercise group (28 ± 17 to 18 ± 12; P < .03), and decreased significantly more in the CPAP group (32 ± 25 to 8 ± 11; P < .007) and in the exercise + CPAP group (25 ± 15 to 10 ± 16; P < .007). Peak oxygen consumption, muscle strength, and endurance improved only with exercise. Both exercise and CPAP improved subjective excessive daytime sleepiness, quality of life, and the New York Heart Association functional class. However, compared with the control group, changes in scores on the 36-item Medical Outcomes Study Short Form Survey and Minnesota Living with Heart Failure Questionnaire were only significant in the exercise groups. Conclusions: In patients with HF and OSA, our preliminary results showed that exercise alone attenuated OSA and improved quality of life more than CPAP. In the landscape treatment of OSA in patients with HF, this analysis is the only randomized trial showing any treatment (in this case, exercise) that improved all the studied parameters. The results highlight the important therapeutic benefits of exercise, particularly because adherence to CPAP is low.
local.identifier.orcidhttp://orcid.org/0000-0002-2919-2806
local.identifier.orcidhttps://orcid.org/0000-0002-2178-1518
local.identifier.orcidhttps://orcid.org/0000-0003-3896-2208
local.identifier.orcidhttps://orcid.org/0000-0002-3361-7061
local.identifier.orcidhttps://orcid.org/0000-0002-9253-6042
local.identifier.orcidhttps://orcid.org/0000-0001-7738-0927
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE ESPORTES
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0012369218307906?via%3Dihub

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