Prevalence of respiratory epithelial adenomatoid hamartomas (reah) associated with nasal polyposis: an epidemiological study - how to diagnose

dc.creatorMaria Julia Abrãoissa
dc.creatorVitor Ramos Ribeiro de Oliveira
dc.creatorFlavio Barbosa Nunes
dc.creatorLuís Otávio Giovanardi Vasconcelos
dc.creatorLuiz Felipe Bartolomeu Souza
dc.creatorGiancarlo Bonotto Cherobin
dc.creatorRoberto Eustáquio Santos Guimarães
dc.date.accessioned2023-07-10T20:04:40Z
dc.date.accessioned2025-09-09T00:10:03Z
dc.date.available2023-07-10T20:04:40Z
dc.date.issued2021-10-10
dc.format.mimetypepdf
dc.identifier.doi10.1016/j.bjorl.2021.09.009
dc.identifier.issn18088694
dc.identifier.urihttps://hdl.handle.net/1843/56041
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBrazilian Journal of Otorhinolaryngology
dc.rightsAcesso Aberto
dc.subjectPólipos Nasais
dc.subjectHamartoma
dc.subject.otherRespiratory epithelial adenomatoid hamartoma
dc.subject.otherNasal polyposis
dc.subject.otherOlfactory cleft
dc.subject.otherNasal computed tomography scan
dc.titlePrevalence of respiratory epithelial adenomatoid hamartomas (reah) associated with nasal polyposis: an epidemiological study - how to diagnose
dc.typeArtigo de periódico
local.citation.spage18088694
local.citation.volume88
local.description.resumoObjectives: To highlight the prevalence of respiratory epithelial adenomatoid hamartomas in the olfactory cleft of patients with nasal polyposis. To demonstrate characteristics indicative of hamartoma on the CT scans of paranasal sinuses during surgery and in histopathological exams. Methods: Cross-sectional study carried out in Hospital das Clínicas da UFMG and Núcleo de Otorrino BH. We performed 114 nasal endoscopic surgeries for polyposis, between February 2015 and November 2019. We assessed the olfactory cleft width in all preoperative CT scans.Upon seeing an indication of hamartoma on the CT scan, we took a tissue sample from the olfactory cleft during the surgery and sent for histopathological exam. We referred the samples to a pathologist experienced in the anatomopathological diagnosis of respiratory epithelial adenomatoid hamartomas. Results: Of the 114 patients with polyposis, 54 (47.4%) had olfactory cleft enlargement and, 100% of them had tissue with a dense and hardened polypoid aspect, with a slight cerebriform appearance in this region during the surgery. Histology confirmed a respiratory epithelial adenomatoid hamartoma. Conclusion: This observation suggests that the presence of hamartomas in polyposis is common, but underdiagnosed.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S180886942100183X?via%3Dihub

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