Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom

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dc.creatorBernar Monteiro Benites
dc.creatorWanessa Miranda-Silva
dc.creatorAndré Caroli Rocha
dc.creatorUla Lindoso Passos
dc.creatorFelipe Paiva Fonseca
dc.creatorCelso Arrais Rodrigues da Silva
dc.creatorEduardo Rodrigues Fregnani
dc.date.accessioned2023-11-24T19:21:35Z
dc.date.accessioned2025-09-08T23:08:13Z
dc.date.available2023-11-24T19:21:35Z
dc.date.issued2021-12-08
dc.identifier.doihttp://dx.doi.org/10.4322/acr.2020.218
dc.identifier.issn22361960
dc.identifier.urihttps://hdl.handle.net/1843/61358
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofAutopsy and Case Reports
dc.rightsAcesso Aberto
dc.subjectB-lymphocytes
dc.subjectBurkitt lymphoma
dc.subjectHypesthesia
dc.subjectRecurrence
dc.subject.otherLinfoma
dc.subject.othernome periódico revista Autopsy and case reports open acess Late recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom assunto Burkitt Lymphoma busca dia 06 do 11 novembro d.c depois de Cristo segunda-feira 2023 fao clínica
dc.titleLate recurrence of burkitt's lymphoma in the jaw: numb chin syndrome as the only symptom
dc.typeArtigo de periódico
local.citation.spagee2020218
local.citation.volume11
local.description.resumoThe Numb Chin Syndrome (NCS) is defined as facial and oral numbness restricted to the mental nerve's distribution involving the lower lip, skin of the chin, or gingiva of the lower anterior teeth. Hypoesthesia can occur unilaterally or bilaterally. Although this syndrome is rare, its importance is related to the fact that it represents the clinical manifestations of malignant diseases. Breast cancer and non-Hodgkin lymphoma are the most common cause of NCS. The patient, a 58-year-old woman, treated for a Burkitt Lymphoma (BL) nine years ago, described a two-week history of change in sensitivity and pain in the chin region, without relief with the use of analgesics. She had no headache, speech disturbance, dysphagia, visual disturbance, or other neurological symptoms. No surgical intervention has been performed recently. The intraoral examination revealed a healthy oral mucosa and a small area adjacent to the right mental nerve region that was uncomfortable to palpation. No changes were found in the bone trabeculae at cone-beam computed tomography. The contrasted magnetic resonance features made it possible to identify a change in the mandibular body extending to the entire right side, coinciding with the patient's complaint, indicating a probable mandibular medullary invasion. The patient was submitted to a biopsy to rule out a possible recurrence of BL. The microscopic findings were consistent with the diagnosis of BL. The present report described a very unusual presentation of late recurrent BL nine years after the first treatment, which manifested as an NCS.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.autopsyandcasereports.org/article/doi/10.4322/acr.2020.218

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