Biocompatibility and biomineralization ability of bio-c pulpecto. a histological and immunohistochemical study

Página do item simplificado
dc.creatorLeopoldo Cosme-Silva
dc.creatorFrancine Benetti
dc.creatorRenan Dal-Fabbro
dc.creatorJoão Eduardo Gomes Filho
dc.creatorVivien Thiemy Sakai
dc.creatorLuciano Tavares Ângelo Cintra
dc.creatorNathalia Alvarez
dc.creatorEdilson Ervolino
dc.creatorNaiana Viana Viola
dc.date.accessioned2022-09-27T19:21:43Z
dc.date.accessioned2025-09-09T01:21:54Z
dc.date.available2022-09-27T19:21:43Z
dc.date.issued2019-01-08
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/ipd.12464
dc.identifier.issn09607439
dc.identifier.urihttps://hdl.handle.net/1843/45623
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational journal of Paediatric Dentistry
dc.rightsAcesso Restrito
dc.subjectBiomineralization
dc.subjectPulpectomy
dc.subjectTooth deciduous
dc.subjectInflammation
dc.subjectOsteocalcin
dc.subjectOsteopontin
dc.subject.otherBioactivity
dc.subject.otherBiomineralization
dc.subject.otherPulpectomy
dc.subject.otherTooth Primary.
dc.titleBiocompatibility and biomineralization ability of bio-c pulpecto. a histological and immunohistochemical study
dc.typeArtigo de periódico
local.citation.epage360
local.citation.issue03
local.citation.spage352
local.citation.volume29
local.description.resumoAim: To evaluate the inflammatory response, biomineralization and production of osteocalcin (OCN), osteopontin (OPN), and bone sialoprotein (BSP) of a new root filling material for primary teeth (Bio-C Pulpecto) compared to MTA. Design: Polyethylene tubes containing Bio-C Pulpecto, MTA, and empty tubes were implanted into the dorsal connective tissue. After 7, 15, 30, 60, and 90 days, the tubes with surrounding tissue were removed and histologically processed to be analysed using haematoxylin and eosin, von Kossa staining, or no staining for observation under polarized light and immunohistochemistry for the detection of OCN, OPN, and BSP. The Kruskal-Wallis test was used followed by Dunn's test. The significance level was set at 5%. Results: The inflammatory response observed with MTA and Bio-C Pulpecto was more exacerbated until the 15th day and decreased from 30 days on. No significant difference was found between control, MTA, and Bio-C Pulpecto (P > 0.05). Bio-C Pulpecto and MTA showed positivity for von Kossa and birefringent to polarized light. The immunolabelling for OCN, OPN, and BSP was more intense for MTA and Bio-C Pulpecto on days 60 and 90 (P > 0.05). Conclusion: Bio-C Pulpecto was biocompatible, induced biomineralization and was immunopositive for osteogenic markers such as OCN, OPN, and BSP, similarly to MTA
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/ipd.12464

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG