Malocclusion characteristics amongst individuals with autism spectrum disorder: a systematic review and meta-analysis

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dc.creatorThiago Peixoto da Motta
dc.creatorJanine Owens
dc.creatorLucas Guimarães Abreu
dc.creatorSuélen Alves Teixeira Debossan
dc.creatorFabiana Vargas Ferreira
dc.creatorMario Vianna Vettore
dc.date.accessioned2025-06-04T16:10:27Z
dc.date.accessioned2025-09-09T01:31:59Z
dc.date.available2025-06-04T16:10:27Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1186/s12903-022-02366-0
dc.identifier.issn14726831
dc.identifier.urihttps://hdl.handle.net/1843/82785
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBMC Oral Health
dc.rightsAcesso Restrito
dc.subjectMalocclusion, angle class II
dc.subjectMalocclusion, angle class III
dc.subjectAutism spectrum disorder
dc.subjectDental care for persons with disabilities
dc.subjectOpen bite
dc.subjectSystematic review
dc.subjectMeta-analysis
dc.subject.otherAutistic disorder
dc.subject.otherMalocclusion, angle class II
dc.subject.otherMalocclusion, angle class III
dc.subject.otherOpen bite
dc.subject.otherSystematic review
dc.subject.otherMeta-analysis
dc.titleMalocclusion characteristics amongst individuals with autism spectrum disorder: a systematic review and meta-analysis
dc.typeArtigo de periódico
local.citation.epage368
local.citation.spage341
local.citation.volume22
local.description.resumoBackground: To estimate the prevalence of malocclusion in individuals with autism spectrum disorders (ASD) and to assess the relationship between ASD and malocclusion. Methods: We searched electronic databases including PubMed, Scopus, Web of Science, Cochrane, Embase, SciELO LILACS, Proquest, OpenGrey and Google Scholar. There were no language or publication dates restrictions. Two researchers independently performed selection, data extraction and quality assessment. Quality assessment and risk of bias were evaluated through the Newcastle–Ottawa scale and ROBINS-E tool. Meta-analyses using random efect models were used to estimate pooled measures of prevalence of malocclusion characteristics in individuals with ASD and pooled odds ratio (OR) on the relationship between ASD and malocclusion characteristics. Subgroup meta-analyses were conducted according to children and adolescents, history of orthodontic treatment, and occurrence of other syndromes and medical conditions. Results: Searching identifed 5549 papers with 238 were selected for full assessment. Eighteen cross-sectional studies were included according to inclusion criteria. Of them, eleven studies were considered of moderate quality. A judgement of critical risk of bias occurred for thirteen studies. The most prevalent malocclusion characteristics in individuals with ASD were crowding (33%; 95% CI 22 to 44%) and increased maxillary overjet (39%; 95% CI 23 to 54%). Individuals with ASD had higher odds of Angle’s Class II (OR 1.92; 95% CI 1.36 to 2.72), Angle’s Class III (OR 2.33; 95% CI 1.29 to 4.23), open bite (OR 1.96; 95% CI 1.21 to 3.16), and increased maxillary overjet (OR 1.53; 95% CI 1.06 to 2.21) than individuals without ASD. Conclusions: Angle’s Class II, Angle’s Class III, anterior open bite and increased maxillary overjet were more prevalent in individuals with ASD than those without ASD. Further high-quality studies are needed.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://www.springermedizin.de/malocclusion-characteristics-amongst-individuals-with-autism-spe/23354596

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