Calcifying epithelial odontogenic tumor: an updated analysis of 339 cases reported in the literature

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dc.creatorBruno Ramos Chrcanovic
dc.creatorRicardo Santiago Gomez
dc.date.accessioned2024-11-14T21:37:49Z
dc.date.accessioned2025-09-09T01:28:33Z
dc.date.available2024-11-14T21:37:49Z
dc.date.issued2017
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.jcms.2017.05.007
dc.identifier.issn1878-4119
dc.identifier.urihttps://hdl.handle.net/1843/78063
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Cranio-Maxillofacial Surgery
dc.rightsAcesso Restrito
dc.subjectWounds and injuries
dc.subjectPrevalence
dc.subjectMandible
dc.subjectRecurrence
dc.subjectErosion
dc.subjectExcision repair
dc.subjectCurettage
dc.subjectTherapeutics
dc.subjectDemography
dc.subject.otherCalcifying epithelial odontogenic tumor
dc.subject.otherClinical features
dc.subject.otherExtraosseous
dc.subject.otherIntraosseous
dc.subject.otherPindborg tumor
dc.subject.otherRecurrence rate.
dc.titleCalcifying epithelial odontogenic tumor: an updated analysis of 339 cases reported in the literature
dc.typeArtigo de periódico
local.citation.epage1123
local.citation.issue8
local.citation.spage1117
local.citation.volume45
local.description.resumoPurpose: The aim of this study was to integrate the available data published on calcifying epithelial odontogenic tumors (CEOT) into a comprehensive analysis of its clinical and radiologic features. Materials and methods: An electronic search was undertaken in May 2016. Eligibility criteria were publications having enough clinical, radiological and/or histological information to confirm definite diagnosis. Results: A total of 362 lesions were found, 339 with enough information were analyzed. Variants clear cells (n = 33) and Langerhans cells (n = 10) were rarely described in the literature, as well as lesions with malignant transformation (n = 8). Central lesions (n = 264) were more prevalent than their peripheral counterparts (n = 24). A higher prevalence characterized the mandible, posterior region, and third and fourth decades. About 40% of the peripheral lesions showed signs of underlying bone erosion, and about half of the central ones showed signs of cortical bone perforation. Recurrence was found in all lesions (12.6%), peripheral lesions (18.8%), central lesions (11.6%), clear cell (10.7%), Langerhans cell (0%), and those with malignant transformation (42.9%). Excision or curettage was associated with the highest recurrence rate. None of the variables showed a statistically significant influence on the recurrence rate. Conclusions: The possible locally aggressive behavior of the lesions recommends a less conservative management than simple curettage. The clear cell variant shows similar demographic data and biological behavior compared to the non-variant lesions, suggesting that the presence of clear cells does not have an important clinical significance.
local.identifier.orcidhttps://orcid.org/0000-0002-3460-3374
local.identifier.orcidhttps://orcid.org/0000-0001-8770-8009
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/abs/pii/S1010518217301634?via%3Dihub

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