Changes in olfaction and taste in patients hospitalized for covid-19 and their relationship to patient evolution during hospitalization

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dc.creatorCarolina c. Marinho
dc.creatorPedro Antônio O.a.gusmão
dc.creatorJosé Reinaldo c. Roveda
dc.creatorAna Sophia m. Leite
dc.creatorArnaldo Santos Leite
dc.date.accessioned2023-10-26T19:29:50Z
dc.date.accessioned2025-09-08T23:45:54Z
dc.date.available2023-10-26T19:29:50Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doi10.1016/j.bjorl.2021.11.002
dc.identifier.issn18088694
dc.identifier.urihttps://hdl.handle.net/1843/60101
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBrazilian Journal of Otorhinolaryngology
dc.rightsAcesso Aberto
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectOlfaction Disorders
dc.subjectTaste Disorders
dc.subject.otherCOVID-19
dc.subject.otherSARS-CoV-2
dc.subject.otherOlfactory disorders
dc.subject.otherTaste disorders
dc.titleChanges in olfaction and taste in patients hospitalized for covid-19 and their relationship to patient evolution during hospitalization
dc.typeArtigo de periódico
local.citation.epageS82
local.citation.issueS5
local.citation.spageS75
local.citation.volume88
local.description.resumoObjectives: During the COVID-19 pandemic, several cases of changes in olfaction and taste associated with the infection have been reported. Therefore, otolaryngologists are frequently the first medical professionals sought by patients. The aim of this study was to evaluate the frequency of olfaction and taste disorders in patients hospitalized with COVID-19, and their association with other clinical manifestations and patient evolution during hospitalization.Methods: 248 patients, admitted to three public hospitals in Belo Horizonte, Minas Gerais,Brazil, were prospectively included: Hospital das Clínicas da Universidade Federal de Minas Gerais (HC-UFMG), Hospital Júlia Kubitschek (HJK) and Hospital Eduardo de Menezes (HEM), who, upon admission to hospital, presented with Severe Acute Respiratory Syndrome due to COVID-19. Clinical and laboratory variables and outcomes during hospitalization were prospectively collected from the electronic medical records. The collection of sociodemographic and symptomatology data during the acute phase was carried out prospectively in electronic medicalrecords and confirmed with the patients at a subsequent outpatient visit.Results: The most frequently reported symptoms were dyspnea (77.4%), cough (69.8%) and fever (55.2%). During the acute phase of the disease, 95 (38.3%) and 87 (35.1%) patients reported taste and olfaction disorders, respectively. There was a lower prevalence of dysosmia among patients with previous comorbidities (p < 0.05). Both symptoms were associated with less need for intensive care admission (p = 0.001 for dysgeusia and p = 0.021 for dysosmia) and a negative correlation with length of hospital stay (dysosmia: r = −0.175, p < 0.05; dysgeusia: r = −0.29, p < 0.001) and length of stay in the ICU (dysosmia: r = −0.136, p < 0.05; dysgeusia: r = −0.215, p < 0.05). The absence of taste disorders was also associated with a greater need for mechanical ventilation (p < 0.001). Conclusion: Changes in taste and olfaction were reported by a large number of patients in the acute phase of COVID-19. In this study, both were markers of better clinical patient evolution.Level of evidence: 1B
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S1808869421001932

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