Photobiomodulation effects on keratinocytes cultured in vitro: a critical review

Página do item simplificado
dc.creatorPriscila Thaís Rodrigues de Abreu
dc.creatorJosé Alcides Almeida de Arruda
dc.creatorRicardo Alves Mesquita
dc.creatorLucas Guimarães Abreu
dc.creatorIvana Márcia Alves Diniz
dc.creatorTarcília Aparecida da Silva
dc.date.accessioned2022-12-20T14:22:59Z
dc.date.accessioned2025-09-09T01:19:31Z
dc.date.available2022-12-20T14:22:59Z
dc.date.issued2019-06-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1007/s10103-019-02813-5
dc.identifier.issn02688921
dc.identifier.urihttps://hdl.handle.net/1843/48246
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofLasers in Medical Science
dc.rightsAcesso Restrito
dc.subjectCytokines
dc.subjectCells
dc.subjectDosimetry
dc.subject.otherDosimetry
dc.titlePhotobiomodulation effects on keratinocytes cultured in vitro: a critical review
dc.typeArtigo de periódico
local.citation.epage1734
local.citation.spage1725
local.citation.volume34
local.description.resumoPhotobiomodulation therapy (PBMT) has been widely used for the promotion of tissue repair. Despite these therapeutic benefits, in some cases, PBMT appears to be unsuccessful, and the strongest hypothesis is that this failure is due to inadequate light dosimetry and wavelengths. The objective of the present critical review was to evaluate the effects of PBMT on cultured keratinocytes using blue, red, or near-infrared light categorized into arbitrary ranges of energy density (0.1–5.0, 5.1–10.0, 10.1–15.0, and over 15.0 J/cm2). The electronic searches were conducted in PubMed, Web of Science, Scopus and LILACS databases, and included LASER or LED devices. A total of 55 articles evaluating the effects of PBMT on cell viability, proliferation, migration, and cytokine and growth factor production were included. Overall, the studies failed to provide detailed information about light dosimetry or detailed experimental conditions. The vast majority of the energy densities tested produced unmodified results regardless of the wavelength applied. However, it was possible to observe that red and near-infrared light had more stimulatory effects than blue light. In addition, for all parameters analyzed, favorable outcomes were mostly obtained in the range of 0.1–5.0 J/cm2. The less explored energy densities were within the 10.1–15.0 J/cm2 range. Energy densities above 15.0 J/cm2 were ineffective or tended to cause cell death. The heterogeneity of the data does not allow us to define a PBMT range setting protocol that would have beneficial effects on keratinocytes
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s10103-019-02813-5

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG