Birth weight is related with bone mineral content in adulthood: results of elsa-brasil

dc.creatorNayranne Hivina Carvalhotavares
dc.creatorCarolina Gomes Coelho
dc.creatorSandhi m. Barreto
dc.creatorLuana Giatti
dc.creatorLarissa Fortunato Araújo
dc.date.accessioned2023-10-30T19:45:44Z
dc.date.accessioned2025-09-08T23:19:20Z
dc.date.available2023-10-30T19:45:44Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doi10.11606/s1518-8787.2022056004064
dc.identifier.issn15188787
dc.identifier.urihttps://hdl.handle.net/1843/60266
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista de Saúde Pública
dc.rightsAcesso Aberto
dc.subjectBone Density
dc.subjectEmbryonic and Fetal Development
dc.subjectSex Distribution
dc.subject.otherBone Density
dc.subject.otherBirth Weigh
dc.subject.otherEmbryonic and Fetal Development
dc.subject.otherSex Distribution
dc.titleBirth weight is related with bone mineral content in adulthood: results of elsa-brasil
dc.typeArtigo de periódico
local.citation.epage10
local.citation.issue103
local.citation.spage1
local.citation.volume56
local.description.resumoOBJECTIVE: To investigate the association between birth weight and bone mineral content (BMC), and whether this relationship differs between men and women. METHODS: A total of 10,159 participants from the ELSA-Brasil cohort were eligible for this analysis. The outcome was the z-score of the ratio BMC (kg)/height (m). The exposure was the low birth weight (< 2.5kg). The magnitude of the associations was estimated by mean differences and their respective 95% confidence intervals (95%CI) using linear regression. All analyses were presented for the total population and stratified by sex. RESULTS: Most were women (54.98%), and the mean age was 52.72 years (SD ± 6.6). In the crude model, we observed that low birth weight was associated with a lower mean BMC/height z-score, compared to adequate birth weight (mean difference: -0.30; 95%CI: -0.39 to -0.21), and this effect was stronger in men (mean difference: -0.43; 95%CI: -0.56 to -0.30) than in women (mean difference: -0.31; 95%CI: -0.44 to -0.19). After adjusting for age, sex per total population, race/skin color, maternal education, individual education, and current weight, there was a considerable reduction in the magnitude of the association (total population: -0.10; 95%CI: -0.14 to -0.06; men: -0.13; 95%CI: -0.21 to -0.06; women: -0.13; 95%CI: -0.21 to -0.05). CONCLUSION: Low birth weight is related to BMC/height z-score in both sexes with no indication of differences by sex. The magnitude of the associations was attenuated after adjustment for the current weight.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIAL
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.11606/s1518-8787.2022056004064

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