Intravascular and intraparenchymatous hepatic segmentary sclerosis
| dc.creator | Guilherme Velloso Diniz | |
| dc.creator | Andy Petroianu | |
| dc.date.accessioned | 2024-01-22T19:00:50Z | |
| dc.date.accessioned | 2025-09-08T22:52:08Z | |
| dc.date.available | 2024-01-22T19:00:50Z | |
| dc.date.issued | 2018 | |
| dc.format.mimetype | ||
| dc.identifier.doi | 10.1590/s0102-865020180090000006 | |
| dc.identifier.issn | 16782674 | |
| dc.identifier.uri | https://hdl.handle.net/1843/63206 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.relation.ispartof | Acta Cirúrgica Brasileira | |
| dc.rights | Acesso Aberto | |
| dc.subject | Liver | |
| dc.subject | Necrosis | |
| dc.subject | Glucose | |
| dc.subject | Hepatectomy | |
| dc.subject | Sclerosis | |
| dc.subject | Dogs | |
| dc.subject.other | Liver | |
| dc.subject.other | Necrosis | |
| dc.subject.other | Glucose | |
| dc.subject.other | Hepatectomy | |
| dc.subject.other | Sclerosis | |
| dc.subject.other | Dogs | |
| dc.title | Intravascular and intraparenchymatous hepatic segmentary sclerosis | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 791 | |
| local.citation.issue | 9 | |
| local.citation.spage | 785 | |
| local.citation.volume | 33 | |
| local.description.resumo | Purpose: To evaluate the morphological effects of injected sclerosing agents into the liver. Methods: This study was performed on twenty dogs, distributed into five groups: Group 1 (n = 5) - control, Group 2 (n = 5) - injection of 50% glucose solution inside hepatic parenchyma and animals followed during seven days, Group 3 (n = 10) - injection of ethanol inside hepatic parenchyma and animals distribution into two subgroups Subgroup 3A (n = 5) - followed during 24 hours and subgroup 3B (n = 5) - followed during seven days (group 3B), Group 4 (n = 5) - ethanol injection inside left portal vein branch and followed during 24 hours. Livers were macroscopically evaluated, submitted to hepatic arteriography and portography, then histology. Results: All animals in Group 4 died within 23 hours due to diffuse hepatic necrosis. The animals of groups 2 and 3 had a satisfactory evolution. Fibrosis formed in the segment reached by the sclerosant solution and interruption of the contrast flow injected into the portal system. Conclusion: Intrahepatic parenchymal ethanol injection is well tolerated and causes sclerosis restricted to a specific segment; however, intraportal ethanol injection causes massive hepatic necrosis and can lead to death. | |
| local.publisher.country | Brasil | |
| local.publisher.department | MED - DEPARTAMENTO DE CIRURGIA | |
| local.publisher.initials | UFMG | |
| local.url.externa | https://doi.org/10.1590/s0102-865020180090000006 |