In vivo biocompatibility and biomineralization of calcium silicate cements

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dc.creatorFrancine Benetti
dc.creatorJoão Eduardo Gomes Filho
dc.creatorJuliana Maria de Araujo Lopes
dc.creatorJéssica Barbosa
dc.creatorRogério Jacinto
dc.creatorLuciano Tavares Ângelo Cintra
dc.date.accessioned2022-09-24T20:28:14Z
dc.date.accessioned2025-09-08T23:00:18Z
dc.date.available2022-09-24T20:28:14Z
dc.date.issued2018-07-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/eos.12539
dc.identifier.issn09098836
dc.identifier.urihttps://hdl.handle.net/1843/45484
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofEuropean Journal of Oral Sciences
dc.rightsAcesso Restrito
dc.subjectDental cements
dc.subjectDental materials
dc.subjectEndodontics
dc.subjectInflammation
dc.subject.otherDental cements
dc.subject.otherDental materials
dc.subject.otherEndodontics
dc.subject.otherInflammation
dc.subject.otherMineral trioxide aggregate
dc.titleIn vivo biocompatibility and biomineralization of calcium silicate cements
dc.typeArtigo de periódico
local.citation.epage333
local.citation.issue04
local.citation.spage326
local.citation.volume126
local.description.resumoA new mineral trioxide aggregate (MTA) material has been developed with a modified composition that requires investigations to support its clinical use. This study evaluated the biocompatibility and biomineralization of this new MTA material and compared it with that of two other MTA cements over time. Tubes containing materials (or empty tubes as controls) were inserted into the subcutaneous tissues of 40 rats. On days 7, 15, 30, 60, and 90, the tubes were removed with the surrounding tissues, which were either stained with haematoxylin and eosin or von Kossa for further analyses or unstained for observation under polarized light. On days 7 and 15, moderate inflammation was observed in most specimens, and the fibrous capsule was thick. On day 30, there was mild inflammation in all groups, and the fibrous capsule was thin. On days 60 and 90, there was mild inflammation in the material groups, while the control group showed no inflammation, although no statistically significant difference between the groups was observed and the fibrous capsule was thin. All material groups showed structures that stained with von Kossa and could be observed under polarized light; this was not found for the control. In conclusion, the new MTA material had biocompatibility and biomineralization properties similar to those of the two existing MTA materials
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/eos.12539

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