Effects of different periods of gastric ischemia on liver as a remote organ

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dc.creatorMaria Angélica Baron
dc.creatorAndy Petroianu
dc.date.accessioned2024-01-22T19:14:45Z
dc.date.accessioned2025-09-09T01:30:11Z
dc.date.available2024-01-22T19:14:45Z
dc.date.issued2018
dc.format.mimetypepdf
dc.identifier.doi10.1590/s0102-865020180110000003
dc.identifier.issn16782674
dc.identifier.urihttps://hdl.handle.net/1843/63210
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofActa Cirúrgica Brasileira
dc.rightsAcesso Aberto
dc.subjectStomach
dc.subjectInflammation
dc.subjectIschemia
dc.subjectLiver
dc.subjectRats
dc.subject.otherStomach
dc.subject.otherIschemia
dc.subject.otherInflammation
dc.subject.otherLiver
dc.subject.otherRats
dc.titleEffects of different periods of gastric ischemia on liver as a remote organ
dc.typeArtigo de periódico
local.citation.epage974
local.citation.issue11
local.citation.spage964
local.citation.volume33
local.description.resumoPurpose: To evaluate the hepatic changes associated with gastric ischemia. Methods: Thirty male rabbits were studied, distributed in 3 groups (n=10). Group 1: ligature and section of the gastric vasculature and removal of the liver after three hours; Group 2: ligature and section of the gastric vasculature and removal of the liver after 6 hours; Group 3: ligature and section of the gastric vasculature and removal of the liver after 12 hours. Blood samples were collected immediately before surgery and after the determined time of ischemia in each group to evaluate the hepatic function. After the death of the rabbits, the liver was removed for macro and microscopic study. Results: An increase in aminotransferases and bilirubin occurred in groups 2 and 3. Total protein and albumin diminished in all of the animals. All of the rabbits from groups 2 and 3 presented hepatocellular necrosis. Conclusion: The devascularization of the stomach for a period of above three hours is associated with hepatic morphological and functional disorders.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/s0102-865020180110000003

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