Oral carcinoma in a patient with systemic sclerosis

dc.creatorAna Carolina Velasco Pondé de Sena
dc.creatorThalita Soares Tavares
dc.creatorFernanda Aragão Felix
dc.creatorSicília Rezende de Oliveira
dc.creatorRayssa Maria Soalheiro de Souza
dc.creatorDenise Vieira Travassos
dc.creatorTarcília Aparecida da Silva
dc.date.accessioned2025-05-20T13:47:36Z
dc.date.accessioned2025-09-08T23:02:17Z
dc.date.available2025-05-20T13:47:36Z
dc.date.issued2023
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2023.03.194
dc.identifier.issn2212-4411
dc.identifier.urihttps://hdl.handle.net/1843/82364
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral surgery, oral medicine, oral pathology and oral radiology
dc.rightsAcesso Restrito
dc.subjectScleroderma, Systemic
dc.subjectHead and neck neoplasms
dc.subjectCarcinoma in situ
dc.subjectAutoimmune diseases
dc.subject.otherSystemic Sclerosis (SSc)
dc.subject.otherOral carcinoma
dc.subject.otherIn situ carcinoma
dc.subject.otherAutoimmune disorder
dc.subject.otherMalignancy risk
dc.titleOral carcinoma in a patient with systemic sclerosis
dc.typeArtigo de periódico
local.citation.epagee60
local.citation.issue1
local.citation.spagee59
local.citation.volume136
local.description.resumoSystemic sclerosis (SSc) is a rare autoimmune connective tissue disorder characterized by fibrosis, vasculopathy, and inflammation. SSc's disease-related characteristics include skin tightness, puffy fingers, open ulcers, and multi-organ involvement. Studies have also identified a higher risk for the development of malignancy in SSc patients. A 56-year-old woman with SSc presented an asymptomatic white plaque of 20 × 25 mm in the right lower lip. Medical history revealed a previous diagnosis of breast cancer and current diagnosis of colorectal cancer. An incisional biopsy was performed, and histological examination showed architectural and cytological atypia of the full epithelial thickness, consistent with those of a severe, in situ dysplasia/carcinoma. The patient was referred to oncology services. Early localized stage diagnosis of in situ carcinoma of the oral cavity brings more favorable prognosis with better overall management, especially in individuals with SSc who presented systemic overlapping complications.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA SOCIAL E PREVENTIVA
local.publisher.initialsUFMG
local.url.externahttps://www.oooojournal.net/article/S2212-4403(23)00305-X/fulltext

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