Glandular odontogenic cyst: an updated analysis of 169 cases reported in the literature
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Objective: To integrate the available data published on glandular odontogenic cyst (GOC) into a comprehensive analysis of its clinical/radiological and histopathological features.
Methods: An electronic search was undertaken in May/2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm the diagnosis.
Results: Fifty-eight publications (169 GOCs) were included. The lesion was slightly more prevalent in men than in women. There was a high prevalence in the fifty/sixth decades of life, in the anterior regions, and in mandibles. Lesions were commonly associated with bone expansion (73%) and unilocular radiological appearance (61.5%). GOC was found to be associated with tooth displacement or an unerupted tooth (30.9%), cortical bone perforation (26%), presence of clinical symptoms (24.3%), root resorption (13.9%). Microscopic parameters most commonly were observed in GOCs-in at least 95% of the lesions: presence of hobnail cells, intraepithelial microcysts, epithelial lining with variable thickness. The presence of apocrine snouting was the microscopic parameter less often found (40.4%).
Conclusion: Although the recurrence rate of GOCs is not as high as previously believed, it is a relevant phenomenon (21.6%). Adjunctive procedures after enucleation should be considered. None of the clinical/radiological and histopathological features evaluated had a statistically significant effect on the recurrence rate.
Abstract
Assunto
Odontogenic cysts, Clinical Study, Radiology, Histology, Tooth avulsion, Root resorption, Signs and symptoms
Palavras-chave
Clinical features, Glandular odontogenic cyst, Odontogenic cysts, Recurrence rate
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https://onlinelibrary.wiley.com/doi/10.1111/odi.12719