The COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study

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dc.creatorRenato T. Souza
dc.creatorSilvana F. Bento
dc.creatorBruna E. Parreira
dc.creatorJosé P. Guida
dc.creatorMário Dias Corrêa Júnior
dc.creatorCaio Leal
dc.creatorRayra Amana
dc.creatorMarcos A. B. Dias
dc.creatorMarcos Nakamura-Pereira
dc.creatorBruna O. Guerra
dc.creatorGabriela Gorga
dc.creatorLeandro de Oliveira
dc.creatorCarla Silveira
dc.creatorKevin F. A. Oliveira
dc.creatorMariana Emi Varicoda Makyama
dc.creatorElias F. Melo Junior
dc.creatorDébora F. Leite
dc.creatorIsabella Monteiro
dc.creatorMarília G. Q. Luz
dc.creatorIsabela R. Pereira
dc.creatorClélia Andrade Salustrino
dc.creatorValéria B. Pontes
dc.creatorRoberto Allen Silva Franco
dc.creatorFernanda G. Surita
dc.creatorJoão Paolo Bilibio
dc.creatorGislânia P. F. Brito
dc.creatorHana Paula C. Pinto
dc.creatorDanielle Leal Oliveira
dc.creatorAndrezza A. Guerra
dc.creatorAndrea O. Moura
dc.creatorNatasha Pantoja
dc.creatorFernanda David
dc.creatorAlina Silva
dc.creatorMaria J. Miele
dc.creatorRicardo P. Tedesco
dc.creatorKarayna G. Fernandes
dc.creatorSérgio H. A. Martins-Costa
dc.creatorFrederico J. A. Peret
dc.creatorFrancisco E. Feitosa
dc.creatorRosiane Mattar
dc.creatorJose G. Cecatti
dc.creatorEvelyn Traina
dc.creatorEdson V. Cunha Filho
dc.creatorJanete Vettorazzi
dc.creatorSamira M. Haddad
dc.creatorCarla B. Andreucci
dc.creatorRodolfo C. Pacagnella
dc.creatorMaria Laura Costa
dc.creatorCarolina C. Ribeiro-do-Valle
dc.creatorAdriana G. Luz
dc.creatorGiuliane J. Lajos
dc.creatorGuilherme M. Nobrega
dc.creatorThayna B. Griggrio
dc.creatorCharles M. Charles
dc.creatorSherly Metelus
dc.creatorLester Castro
dc.creatorStephanie Pabon
dc.creatorAmanda D. Silva
dc.creatorPaulo S. R. Junior
dc.creatorThais G. Sardinha
dc.creatorRodolfo R. Japenga
dc.creatorErica R. F. Urquiza
dc.creatorMaíra R. Machado
dc.creatorMarcela Maria Simões
dc.creatorLarissa M. Solda
dc.creatorJuliana Vasconcellos Freitas-Jesus
dc.creatorRachel Esteves Soeiro
dc.creatorPatrícia B. Peres
dc.creatorCristiane L. Arbeli
dc.creatorRafael M. Quevedo
dc.creatorCarolina F. Yamashita
dc.creatorJulia D. Corradin
dc.creatorIsabella Bergamini
dc.creatorJosé Geraldo L. Ramos
dc.creatorMaria Lúcia R. Oppermann
dc.creatorLaisa S. Quadro
dc.creatorLina Marins
dc.creatorÉrika V. Paniz
dc.creatorThaís Vicentini Xavier
dc.creatorMarina H. L. Almeida
dc.creatorBruna F. V. Moura
dc.creatorLidiane R. França
dc.creatorHanna Vieira
dc.creatorRafael B. Aquino
dc.creatorThayna B. Griggio
dc.creatorAline C. Costa
dc.creatorDaisy Pinheiro
dc.creatorDenise Cordeiro
dc.creatorPriscila L. Miná
dc.creatorCarol Dornellas
dc.creatorSue Yazaki-sun
dc.creatorPriscilla Mota
dc.creatorArimaza C. Soares
dc.creatorEdson V. Cunha Filho
dc.creatorEllen Machado
dc.creatorAnne Bergmann
dc.creatorGustavo Raupp Santos
dc.creatorAline Tosetto
dc.creatorSabrina Savazoni
dc.date.accessioned2023-12-07T21:26:54Z
dc.date.accessioned2025-09-08T23:40:02Z
dc.date.available2023-12-07T21:26:54Z
dc.date.issued2022-07-11
dc.description.sponsorshipOutra Agência
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1038/s41598-022-15647-z
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/1843/61844
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofScientific Reports
dc.rightsAcesso Aberto
dc.subjectCOVID-19
dc.subjectGravidez
dc.subjectBrasil
dc.subjectPeríodo Pós-Parto
dc.subject.otherCOVID-19
dc.subject.otherGravidez
dc.subject.otherBrasil
dc.subject.otherPeríodo Pós-Parto
dc.titleThe COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study
dc.typeArtigo de periódico
local.citation.epage14
local.citation.issue1
local.citation.spage11758
local.citation.volume12
local.description.resumoBrazil presented a very high number of maternal deaths and evident delays in healthcare. We aimed at evaluating the characteristics of SARS-CoV-2 infection and associated outcomes in the obstetric population. We conducted a prospective cohort study in 15 Brazilian centers including symptomatic pregnant or postpartum women with suspected COVID-19 from Feb/2020 to Feb/2021. Women were followed from suspected infection until the end of pregnancy. We analyzed maternal characteristics and pregnancy outcomes associated with confirmed COVID-19 infection and SARS, determining unadjusted risk ratios. In total, 729 symptomatic women with suspected COVID-19 were initially included. Among those investigated for COVID-19, 51.3% (n = 289) were confirmed COVID-19 and 48% (n = 270) were negative. Initially (before May 15th), only 52.9% of the suspected cases were tested and it was the period with the highest proportion of ICU admission and maternal deaths. Non-white ethnicity (RR 1.78 [1.04–3.04]), primary schooling or less (RR 2.16 [1.21–3.87]), being overweight (RR 4.34 [1.04–19.01]) or obese (RR 6.55 [1.57–27.37]), having public prenatal care (RR 2.16 [1.01–4.68]), planned pregnancies (RR 2.09 [1.15–3.78]), onset of infection in postpartum period (RR 6.00 [1.37–26.26]), chronic hypertension (RR 2.15 [1.37–4.10]), pre-existing diabetes (RR 3.20 [1.37–7.46]), asthma (RR 2.22 [1.14–4.34]), and anaemia (RR 3.15 [1.14–8.71]) were associated with higher risk for SARS. The availability of tests and maternal outcomes varied throughout the pandemic period of the study; the beginning was the most challenging period, with worse outcomes. Socially vulnerable, postpartum and previously ill women were more likely to present SARS related to COVID-19.
local.identifier.orcidhttps://orcid.org/0000-0003-4198-0546
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIA
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.url.externahttps://www.nature.com/articles/s41598-022-15647-z

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