Systemic mastocytosis with terminal leukemic manifestation in two dogs

Página do item simplificado
dc.creatorRoselene Ecco
dc.creatorAnna L. F. V. Assumpção
dc.creatorRodrigo de Macedo Couto
dc.creatorRachel L. A. L. T. Neto
dc.creatorPâmela Cristina Lopes Gurgel Valente
dc.creatorConrado O. Gamba
dc.creatorFabiola de Oliveira Paes Leme
dc.creatorPaulo Ricardo de Oliveira Paes
dc.date.accessioned2024-04-15T19:53:25Z
dc.date.accessioned2025-09-09T01:33:27Z
dc.date.available2024-04-15T19:53:25Z
dc.date.issued2017
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doihttp://bjvp.org.br/wp-content/uploads/2017/11/v10-n3-5.pdf
dc.identifier.issn1983-0246
dc.identifier.urihttps://hdl.handle.net/1843/67191
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBrazilian Journal of Veterinary Pathology
dc.rightsAcesso Aberto
dc.subjectMedula óssea
dc.subjectHistopatologia
dc.subjectLeucemia de mastócitos
dc.subjectMastocitose
dc.subject.otherBone marrow
dc.subject.otherc-KIT
dc.subject.otherHistopathology
dc.subject.otherMast cell leukemia
dc.subject.otherMastocytosis
dc.titleSystemic mastocytosis with terminal leukemic manifestation in two dogs
dc.typeArtigo de periódico
local.citation.epage123
local.citation.issue3
local.citation.spage117
local.citation.volume10
local.description.resumoSystemic mastocytosis (SM) with leukemic manifestation is rarely reported in veterinary patients. Here, we describe two cases of systemic mastocytosis with leukemic spread of neoplastic mast cells in adult dogs, including their clinical signs, clinical and anatomic pathology, and immunohistochemical analysis of c-KIT as a diagnostic tool. In both cases, hematologic examination revealed normocytic and normochromic anaemia, leucocytosis with segmented neutrophils, and mastocytosis. Cytological analyses of the peritoneal fluid revealed many neoplastic mast cells. Case 1 was associated with a subcutaneous mast cell tumor and Case 2 was not associated with a cutaneous or subcutaneous mast cell tumor. Neoplastic mast cells were found in the lymph nodes, spleen, liver, and kidneys, and a diagnosis of visceral mastocytosis was established. SM with terminal leukemic manifestation was confirmed by the mastocythemia intensity associated with the morphological changes of the mast cells in the blood and bone marrow.
local.identifier.orcidhttps://orcid.org/0000-0002-8052-5389
local.identifier.orcidhttps://orcid.org/0009-0003-9218-060X
local.identifier.orcidhttps://orcid.org/0000-0002-2035-8961
local.identifier.orcidhttps://orcid.org/0000-0002-4013-0147
local.identifier.orcidhttps://orcid.org/0000-0002-1366-7352
local.publisher.countryBrasil
local.publisher.departmentVET - DEPARTAMENTO DE CLÍNICA E CIRURGIA
local.publisher.initialsUFMG
local.url.externahttps://bjvp.org.br/vol-10-n-3-november-2017/

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Systemic mastocytosis with terminal leukemic manifestation in two dogs.pdf
Tamanho:
623.68 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG