Koh group influence on titanium surfaces and pure sol-gel silica for enhanced osteogenic activity

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dc.creatorRodrigo Porto Guimarães
dc.creatorAllyson Nogueira Moreira
dc.creatorLudmila Gonçalves de Oliveira Xavier
dc.creatorKátia Lucy de Melo Maltos
dc.creatorAna Flor Sá
dc.creatorRosana Zacarias Domingues
dc.creatorVagner Eustáquio de Carvalho
dc.creatorDaniel Cunha Elias
dc.creatorJosé Augusto César Discacciati
dc.creatorCinthia Mara da Fonseca Pacheco
dc.date.accessioned2022-10-17T21:06:44Z
dc.date.accessioned2025-09-09T00:59:34Z
dc.date.available2022-10-17T21:06:44Z
dc.date.issued2020
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.format.mimetypepdf
dc.identifier.doi10.1177/0885328220934323
dc.identifier.issn08853282
dc.identifier.urihttps://hdl.handle.net/1843/46282
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Biomaterials Applications
dc.rightsAcesso Restrito
dc.subjectDental implants
dc.subjectOsteoblasts
dc.subjectTitanium
dc.subject.otherDental implants
dc.subject.otherBioactive glass
dc.subject.othercellular uptake
dc.subject.otherOsteoblasts
dc.subject.otherSurface modification
dc.titleKoh group influence on titanium surfaces and pure sol-gel silica for enhanced osteogenic activity
dc.typeArtigo de periódico
local.citation.epage421
local.citation.issue3
local.citation.spage405
local.citation.volume35
local.description.resumoAlthough, the excellent level of success of titanium surfaces is based on the literature, there are some biological challenges such as unfavorable metabolic conditions or regions of poor bone quality where greater surface bioactivity is desired. Seeking better performance, we hypothesized that silica-based coating via sol-gel route with immersion in potassium hydroxide basic solution induces acceleration of bone mineralization. This in vitro experimental study coated titanium surfaces with bioactive glass synthesized by route sol-gel via hydrolysis and condensation of chemical alkoxide precursor, tetraethylorthosilicate (TEOS) and/or deposition of chemical compound potassium hydroxide (KOH) to accelerate bone apposition. The generated surfaces titanium(T), titanium with potassium hydroxide deposition (T + KOH), titanium with bioactive glass deposition synthesized by sol-gel route via tetraethylorthosilicate hydrolysis (TEOS), titanium with bioactive glass deposition synthesized by sol-gel route via tetraethylorthosilicate hydrolysis with potassium hydroxide deposition (TEOS + KOH) were characterized by 3D optical profilometry, scanning electron microscopy (SEM), transmission electron microscopy (TEM), contact angle by the sessile drop method, x-ray excited photoelectron spectroscopy (XPS) and energy dispersive x-ray spectrometer (EDX). The addition of the KOH group on the pure titanium (T) or bioactive glass (TEOS) surfaces generated a tendency for better results for mineralization. Groups covered with bioactive glass (TEOS, TEOS + KOH) tended to outperform even groups with titanium substrate (T, T + KOH). The addition of both, bioactive glass and KOH, in a single pure titanium substrate yielded the best results for the mineralization process
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
local.publisher.departmentFAO - FACULDADE DE ODONTOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://journals.sagepub.com/doi/10.1177/0885328220934323?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

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