Aggregatibacter actinomycetemcomitans serotypes and JP2 outcomes related to clinical status over 6 years under periodontal maintenance therapy

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dc.creatorJosé Roberto Cortelli
dc.creatorSheila Cavalca Cortelli
dc.creatorDavi Romeiro Aquino
dc.creatorTaís Browne Miranda
dc.creatorJoão Carlos Moreira Jardim
dc.creatorFernando de Oliveira Costa
dc.date.accessioned2024-06-11T20:05:23Z
dc.date.accessioned2025-09-09T01:32:06Z
dc.date.available2024-06-11T20:05:23Z
dc.date.issued2020-08
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1016/j.archoralbio.2020.104747
dc.identifier.issn00039969
dc.identifier.urihttps://hdl.handle.net/1843/69135
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArchives of Oral Biology
dc.rightsAcesso Restrito
dc.subjectAggregatibacter actinomycetemcomitans
dc.subjectCompliance
dc.subjectExotoxins
dc.subjectPorphyromonas gingivalis
dc.subjectLongitudinal studies
dc.subjectTannerella forsythia
dc.subjectTreponema denticola
dc.subjectSerogroup
dc.subjectTherapeutics
dc.subject.otherAggregatibacter actinomycetemcomitans
dc.subject.otherserotypes acesso restrito título periódico:Archives of Oral Biology busca dia 27/05/2024 mês maio ano d.c depois de Cristo.assunto Aggregatibacter actinomycetemcomitans. fao clínica. Aggregatibacter actinomycetemcomitans serotypes and jp2 outcomes related to clinical status over 6 years under periodontal maintenance therapy
dc.subject.otherJP2 clone of Aggregatibacter actinomyctemcomitans
dc.subject.otherPeriodontal Maintenance Therapy
dc.titleAggregatibacter actinomycetemcomitans serotypes and JP2 outcomes related to clinical status over 6 years under periodontal maintenance therapy
dc.typeArtigo de periódico
local.citation.epageX
local.citation.spage104747
local.citation.volume116
local.description.resumoObjective: This 6-year study evaluatedAggregatibacter actinomycetemcomitans outcomes and their relationship to clinical status. Design: From the eligible individuals (23-70 years of age), 31 regular compliers (between-visit interval < 6 months) were randomly selected and matched for age/sex with 31 irregular compliers (between-visit interval > 6 months). Periodontal clinical examination and subgingival samples were obtained 5 times: T1 (baseline), T2 (after active periodontal therapy), T3 (2 years), T4 (4 years), and T5 (6 years). Total bacteria load, A. actinomycetemcomitans, and red complex species Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola levels were determined by qPCR while PCR was used to determine the occurrence of the a-b-c-d-e-f-g serotypes and the JP2 clone of A. actinomycetemcomitans. Data between groups was compared over time. Results: At baseline PCR revealed A. actinomycetemcomitans prevalence of 9.7 % and JP2 prevalence of 6.7 %. A. actinomycetemcomitans qPCR levels were higher among individuals < 35 years of age and increased at T2 in irregular compliers. At in irregular compliers at the three follow-up visits. Serotypes a, d, and f showed greater values in at least one follow-up visit in regular compliers. A. actinomycetemcomitans showed negative correlation with probing depth (PD) while serotype b showed negative correlations with PD, PI, clinical attachment level and red complex. Conclusions: Longitudinally, compliance during PMT contributed to lower A. actinomycetemcomitans levels with some degree of correlation with clinical status. However, this study failed to report any positive effect on the occurrence of the most virulent representatives, i.e. serotype b and the JP2 clone.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0003996920301254?via%3Dihub

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