Health-related quality of life reported by patients with chagas disease: a systematic review of qualitative evidence with grade recommendations

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dc.creatorWhesley Tanorsilva
dc.creatorMauro Felippe Felix Mediano
dc.creatorManoel Otávio da Costa Rocha
dc.creatorHenrique Silveira Costa
dc.creatorLucas Frois Fernandes Oliveira
dc.creatorDiego Mendes Xavier
dc.creatorPedro Henrique Scheidt Figueiredo
dc.creatorAna Cristina Rodrigues Lacerda
dc.creatorVanessa Amaral Mendonça
dc.creatorMatheus Ribeiro Ávila
dc.creatorCláudio Luiz Ferreira Júnior
dc.creatorMárcia Maria Oliveira Lima
dc.date.accessioned2024-01-11T19:06:00Z
dc.date.accessioned2025-09-08T23:55:26Z
dc.date.available2024-01-11T19:06:00Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0377-2022
dc.identifier.issn16789849
dc.identifier.urihttps://hdl.handle.net/1843/62639
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical
dc.rightsAcesso Aberto
dc.subjectChagas disease
dc.subjectQuality of life
dc.subjectQualitative Research
dc.subjectSystematic Review
dc.subject.otherChagas disease
dc.subject.otherQuality of life
dc.subject.otherQualitative Research
dc.subject.otherSystematic Review
dc.titleHealth-related quality of life reported by patients with chagas disease: a systematic review of qualitative evidence with grade recommendations
dc.typeArtigo de periódico
local.citation.epage8
local.citation.issuee0377-2022
local.citation.spage1
local.citation.volume55
local.description.resumoPatients with Chagas disease have reduced health-related quality of life (HRQoL). Hence, we aimed to identify the factors that mostly affected their HRQoL. This was a systematic review of qualitative studies. The Latin American and Caribbean Health Sciences Literature, Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Web of Science, and SciVerse Scopus databases were searched for relevant studies without language or date restrictions. The search and data analysis were performed by independent reviewers; all qualitative studies that reported the factors that had an impact on the HRQoL of patients with Chagas disease were included. The risk of bias was assessed using the Critical Appraisal Skills Program Qualitative Study Checklist; confidence in the evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation-Confidence in the Evidence from Reviews of Qualitative approach. Five studies were included in this review: four in Brazil and one in California, United States, with immigrants from Central and South America. The sample consisted of 207 patients with chronic Chagas disease. Stigma, physical limitations, work absenteeism, emotional or mental aspects, fear of treatment, and fear of the future had the strongest impact on the HRQoL. All items showed moderate confidence except for fear of treatment (low confidence). The physical, emotional, mental, and cultural aspects affected the HRQoL of patients with chronic Chagas disease. Identification of these factors is important in the development of strategies aimed at improving the HRQoL of this population.
local.publisher.countryBrasil
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0037-8682-0377-2022

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