Prevalence of latent mycobacterium tuberculosis infection in renal transplant recipients

dc.creatorMônica Maria Moreira Delgadomaciel
dc.creatorMaria Das Graças Braga Ceccato
dc.creatorWânia da Silva Carvalho
dc.creatorPedro Daibert de Navarro
dc.creatorKátia de Paula Farah
dc.creatorSilvana Spindola de Miranda
dc.date.accessioned2023-12-11T20:17:32Z
dc.date.accessioned2025-09-09T01:07:01Z
dc.date.available2023-12-11T20:17:32Z
dc.date.issued2018
dc.format.mimetypepdf
dc.identifier.doi10.1590/s1806-37562017000000367
dc.identifier.issn18063756
dc.identifier.urihttps://hdl.handle.net/1843/61882
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJornal Brasileiro de Pneumologia
dc.rightsAcesso Aberto
dc.subjectTuberculosis
dc.subjectTuberculin Test
dc.subjectImmunocompromised Host
dc.subject.otherTuberculosis
dc.subject.otherTuberculin Test
dc.subject.otherImmunocompromised Host
dc.titlePrevalence of latent mycobacterium tuberculosis infection in renal transplant recipients
dc.typeArtigo de periódico
local.citation.epage468
local.citation.issue6
local.citation.spage461
local.citation.volume44
local.description.resumoObjective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patients aged ≥ 18 years who underwent renal transplantation at the Renal Transplant Center of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. We included renal transplant recipients who underwent the TST between January 2011 and July 2013. If the result of the fi rst TST was negative, a second TST was administered. Bivariate and multivariate analyses using logistic regression were used to determine factors associated with positive TST results. Results: The sample included 216 patients. The prevalence of LTBI was 18.5%. In the multivariate analysis, history of contact with a tuberculosis case and preserved graft function (estimated glomerular fi ltration rate ≥ 60 mL/min/1.73 m2) were associated with positive TST results. TST induration increased by 5.8% from the first to the second test, which was considered signifi cant (p = 0.012). Conclusions:The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the fi rst TST is negative.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIAL
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/S1806-37562017000000367

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